Frontoparietal connectivity, Sensory Features, and Anxiety in Children and Adolescents with Autism Spectrum Disorder
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Published:2022-08-05
Issue:1
Volume:7
Page:14-26
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ISSN:2366-7532
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Container-title:Advances in Neurodevelopmental Disorders
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language:en
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Short-container-title:Adv Neurodev Disord
Author:
Sarmukadam Kimaya, Bitsika Vicki, Sharpley Christopher F.ORCID
Abstract
Abstract
Objectives
Because atypical global neural connectivity has been documented in autistic youth, but only limited data are available regarding the association between generalized anxiety disorder (GAD), sensory features (SF), and neural connectivity between frontal and parietal brain regions, these links were investigated in a sample of male autistic children and adolescents.
Methods
Forty-one autistic males aged between 6 and 18 years and their mothers were recruited as volunteer participants from Queensland, Australia. Participants underwent 3 min of eyes-closed and 3 min of eyes-opened electroencephalography (EEG) under resting conditions. EEG connectivity was investigated using Granger causality between frontal and parietal regions in alpha (8–13 Hz) and beta (13–30 Hz) bands.
Results
There was a significant (p < .01) positive correlation between SF and GAD. GAD was associated with some characteristics of SF in the sample population. Additionally, there was a significant (p < .01) inverse correlation between directional frontoparietal connectivity and SF during the eyes-closed condition, specifically in relation to avoiding stimuli and sensitivity to the environment.
Conclusions
Reduced frontoparietal connectivity in association with higher anxiety and SF may demonstrate reduced relaxation due to greater sensitivity to sensory input.
Funder
University of New England
Publisher
Springer Science and Business Media LLC
Subject
Psychology (miscellaneous),Social Sciences (miscellaneous)
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