1. Davenport HW: Destruction of mucosal barrier by detergents and urea. Gastroenterology 54:175–182, 1968. Classical paper on definition and properties of the gastric mucosal barrier.
2. Ritchie WP: Bile acids, the “barrier”, and reflux-related clinical disorders of the gastric mucosa. Surgery 82:192–200, 1977. Paper with original data suggesting that bile acid reflux may be responsible for gastritis and barrier-breaking.
3. Duane WC, Wiegand DM, Siebert CE: Bile acid and bile salt disrupt gastric mucosal barrier by different mechanisms. Am J Physiol 242:G95–G99, 1982.In vitro study demonstrating effects of bile acids on the gastric mucosal barrier.
4. Black RB, Hole D, Rhodes J: Bile damage to gastric mucosal barrier: The influence of pH and bile acid concentration. Gastroenterology 61:178–184, 1971. Paper showing gastric mucosal injury by bile, as well as concentration-and pH-dependence of the damaging effect.
5. Geall MG, Phillips SF, Summerskill WHJ: The profile of gastric potential difference in man: Effect of aspirin, alcohol, bile and exogenous acid. Gastroenterology 58:437–442, 1970. Original paper demonstrating effects of aspirin on transmural gastric potential difference in humans.