Therapy of Gastric Ulcer Disease

Author:

Lam Shiu Kum

Publisher

Springer US

Reference37 articles.

1. Mayberry JF, Williams RA, Rhodes J, et al: A controlled clinical trial of sucralfate in the treatment of gastric ulcer. Br J Clin Pract 32:291–293, 1978. This study used radiological assessment of healing; no exclusion criteria were presented; two patients in each group were on analgesic.

2. Rhodes J, Mayberry JF, Williams FA, et al: Clinical trial of sucralfate in the treatment of gastric ulcer, in Caspary WF (ed): Duodenal Ulcer, Gastric Ulcer: Sucralfate, a New Therapeutic Concept. Sucralfate Symposium, 11th International Congress of Gastroenterology, Hamburg, June 1980. Munich, Urban &0026; Schwarzenberg, 1981, pp 101–104. This study used radiological assessment and was unable to show any statistically significant advantage with sucralfate.

3. Fixa B, Komarkova O: Aluminum sucrose sulphate (sucralfate) in the treatment of peptic ulcer (double-blind study), in Caspary WF (ed): Duodenal Ulcer, Gastric Ulcer: Sucralfate, a New-Therapeutic Concept. Sucralfate Symposium, 11th International Congress of Gastroenterology, Hamburg, June 1980. Munich, Urban &0026; Schwarzenberg, 1981, pp 80–84. This placebo-controlled study showed that sucralfate healed gastric ulcer significantly better than placebo.

4. Orchard R, Elliot C: A double-blind placebo-controlled study of sucralfate in the treatment of gastric and duodenal ulcer, in Caspary WF (ed): Duodenal Ulcer, Gastric Ulcer: Sucralfate, a New Therapeutic Concept. Sucralfate Symposium, 11th International Congress of Gastroenterology, Hamburg, June 1980. Munich, Urban &0026; Schwarzenberg, 1981, pp 85–88. Because only a total of 21 patients were evaluated, this study showed only a trend in favor of sucralfate.

5. Ishimori A, Arakawa H: A placebo-controlled, double-blind trial using sucralfate for the treatment of peptic ulcer: A multicenter Japanese study, in Caspary WF (ed): Duodenal Ulcer, Gastric Ulcer: Sucralfate, a New Therapeutic Concept. Sucralfate Symposium, 11th International Congress of Gastroenterology, Hamburg, June 1980. Munich, Urban &0026; Schwarzenberg, 1981, pp 93–100. This large-scale study involving close to 140 patients showed significant healing efficacy with sucralfate.

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