Cerebral and blood pharmacokinetics of imipramine and its active metabolites in the pregnant rat

Author:

DeVane Lindsay C.,Simpkins James W.,Stout Susan A.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology

Reference29 articles.

1. Bickel MH, Weder HJ (1968) The total fate of a drug: Kinetics of distribution, excretion, and formation of 14 metabolites in rats treated with imipramine. Arch Int Pharmacodyn Ther 173:433?463

2. Brodie BB, Bickel MH, Sulser F (1961) Desmethylimipramine, a new type of antidepressant drug. Med Exp 5:454?458

3. Casper R, Garver DL, Dekirmenjian H, Chang S, Davis JM (1980) Phenothiazine levels in plasma and red blood cells. Arch Gen Psychiatry 37:301?305

4. Daniel W, Adamus A, Melzyacka M, Szymura J, Vetulani J (1981) Cerebral pharmacokinetics of imipramine in rats after single and multiple doses. Arch Pharmacol 317:209?213

5. DeVane CL, Jusko WJ (1981) Plasma-concentration monitoring of hydroxylated metabolites of imipramine and desipramine. Drug Intell Clin Pharm 15:263?266

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