Selection against blood cells deficient in hypoxanthine phosphoribosyltransferase (HPRT) in Lesch-Nyhan heterozygotes occurs at the level of multipotent stem cells-Reference-Cited by-同舟云学术

Selection against blood cells deficient in hypoxanthine phosphoribosyltransferase (HPRT) in Lesch-Nyhan heterozygotes occurs at the level of multipotent stem cells

Published:1995-12 Issue:6 Volume:96 Page:674-680
ISSN:0340-6717
Container-title:Human Genetics
language:en
Short-container-title:Hum Genet

Author:

Hakoda Masayuki,Hirai Yuko,Akiyama Mitoshi,Yamanaka Hisashi,Terai Chihiro,Kamatani Naoyuki,Kashiwazaki Sadao

Publisher

Springer Science and Business Media LLC

Subject

Genetics (clinical),Genetics

Link

http://link.springer.com/content/pdf/10.1007/BF00210298.pdf

Reference36 articles.

1. Albertini RJ, Castle KL, Borcherding WR (1982) T-cell cloning to detect the mutant 6-thioguanine-resistant lymphocytes present in human peripheral blood. Proc Natl. Acad Sci USA 79:6617?6621

2. Albertini RJ, O'Neill JP, Nicklas JA, Heintz NH, Kelleher P (1985) Alterations of the hprt gene in human in vivo-derived 6-thioguanine-resistant T lymphocytes. Nature 316:369?371

3. Allison AC, Watts WE, Hovi T, Webster ADB (1975) Immunological observations on patients with Lesch-Nyhan syndrome, and on the role of de-novo purine synthesis in lymphocyte transformation. Lancet II:1179?1182

4. Bradley WEC, Gareau JLP, Seifert AM, Messing K (1987) Molecular characterization of 15 rearrangements among 90 human in vivo somatic mutants shows that deletions predominate. Mol Cell Biol 7:956?960

5. Davies MJ, Lovell DP, Anderson D (1992) Thioguanine-resistant mutant frequency in T-lymphocytes from a healthy human population. Mutat Res 265:165?171

Cited by 23 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT);Environmental and Molecular Mutagenesis;2024-06-03

2. Purine Nucleotide Alterations in Tumoral Cell Lines Maintained with Physiological Levels of Folic Acid;International Journal of Molecular Sciences;2023-08-08

3. Dosage Compensation in Females with X-Linked Metabolic Disorders;International Journal of Molecular Sciences;2021-04-26

4. Perfecting a high hypoxanthine phosphoribosyltransferase activity–uricase KO mice to test the effects of purine‐ and non‐purine‐type xanthine dehydrogenase (XDH) inhibitors;British Journal of Pharmacology;2020-02-18

5. Skewed X inactivation in Lesch–Nyhan disease carrier females;Journal of Human Genetics;2017-09-14