Clinical practice selectively follows acute appendicitis guidelines
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Published:2023-01-31
Issue:1
Volume:49
Page:45-56
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ISSN:1863-9933
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Container-title:European Journal of Trauma and Emergency Surgery
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language:en
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Short-container-title:Eur J Trauma Emerg Surg
Author:
Bass Gary Alan, Mohseni ShahinORCID, Ryan Éanna J., Forssten Maximilian Peter, Tolonen Matti, Cao Yang, Kaplan Lewis J., Ahl Hulme Rebecka, Biloslavo Alan, Kurihara Hayato, Martinez-Casas Isidro, Pereira Jorge, Pourlotfi Arvid, Louri NayefORCID, Cao Yang, Nedham FatemaORCID, Walsh Thomas NoelORCID, Hashem Jamal, Corbally MartinORCID, Farhan AbeerORCID, Al Hamad HamadORCID, Elhennawy RawanORCID, AlKooheji MariamORCID, AlYusuf ManarORCID, Aknouche WissalORCID, Zeidan Anas A.ORCID, Alsaffar Yusuf S.ORCID, Lipping EdgarORCID, Talving PeepORCID, Saar StenORCID, Graumann KatrinaORCID, Kibuspuu LiisORCID, Harkov EduardORCID, Aaltonen GiseleORCID, Sillman Iines S.ORCID, Haapanen SamiORCID, Lampela HannaORCID, Sammalkorpi HennaORCID, Eskola SofiaORCID, Laakso AlttiORCID, Back JohanORCID, Kettunen UllaORCID, Nummi Antti M.ORCID, Szwedyc AnikaORCID, Nykänen TainaORCID, Rantala RolleORCID, Mäkäräinen-Uhlbäck Elisa J.ORCID, Meriläinen Sanna A.ORCID, Huhta Heikki I.ORCID, Rintala Jukka M. J.ORCID, Laitakari Kirsi E. M.ORCID, Lietzen ElinaORCID, Salminen PaulinaORCID, Rapola Risto K. A.ORCID, Zangouri Vahid, Karami Mohammad Y., Tahmasebi Sedigheh, Akrami Majid, Golchini Alireza, Bahrami Faranak, Johnston Sean M.ORCID, Lim Sean T.ORCID, Ahonkhai Irele IfijehORCID, Eltagani EltahirORCID, Ryan Odhran K., O’Driscoll-Collins AilbheORCID, O’Neill AineORCID, Penny ZakiyaORCID, Kelly OrlaithORCID, Cullinane CarolynORCID, Reynolds IanORCID, Heneghan HelenORCID, Martin SeanORCID, Winter Des, Davey Matthew, Alkhattab Maha, Lowery Aoif J., Kerin Michael J., Hogan Aisling M, Davey Martin S, Oh Ke En, Kabir Syed Mohammad UmarORCID, Huan HuilunORCID, Aziz CharlotteORCID, Sugrue MichaelORCID, Ryan Jessica M.ORCID, Connelly Tara M.ORCID, Alhazmi MohammadORCID, Al-Mukhaizeem YoussefORCID, Cooke FiachraORCID, Neary Peter M.ORCID, Hill Arnold D. K.ORCID, Boland Michael R.ORCID, Lloyd Angus J.ORCID, Fallon FrancesORCID, Cleere Eoin F.ORCID, Toale JamesORCID, Boland Patrick A., Devine Michael, Keady Conor, Hunter Sarah, Barry M. Kevin, Kelly Michael E.ORCID, O’Dowling Aidan T.ORCID, Creavin BenORCID, Kavanagh Dara O.ORCID, Neary PaulORCID, Ridgway Paul F F.ORCID, McCarrick Cathleen A.ORCID, Bolger Jarlath, Maguire Barry, Keogh Cian, Chawla Surbhi, Conneely JohnORCID, McCormack EmilieORCID, Shanahan BenORCID, Raftery NicolaORCID, Rice DarraghORCID, McInerney NiallORCID, Stakelum AineORCID, Mares JanORCID, Tan JonavanORCID, Hanna MarkORCID, Balasubramanian IshwaryaORCID, Fleming ChristinORCID, Barsky GuyORCID, Shaked GadORCID, Giudici Simone, Ceolin MartinaORCID, Mei SimonaORCID, Mazzarella FrancescaORCID, Zucca AnnalisaORCID, Terranova SusannaORCID, de Manzini NicoloORCID, Visconti DiegoORCID, Doria EmanueleORCID, Santarelli Mauro, Scotton GiovanniORCID, Notte FrancescaORCID, Bertelli GiacomoORCID, Malpaga AnnaORCID, Armatura GiuliaORCID, Frena AntonioORCID, Tartaglia DarioORCID, Coccolini FedericoORCID, Cremonini CamillaORCID, Cicuttin EnricoORCID, Mazzoni AlessioORCID, Chiarugi MassimoORCID, Azevedo Constança M.ORCID, Mendes Filipa D.ORCID, Faria Luis Q.ORCID, Nazario CarlosORCID, Machado DanielaORCID, Semiao MiguelORCID, Casimiro Carlos, Pinto Jose, Pavão Tiago, Pereira Raquel, Barbosa Bruno, Tenreiro NadiaORCID, Ferreira CatiaORCID, Guidi GoncaloORCID, Martins Daniela C.ORCID, Leal ClaraORCID, Vieira Bruno B.ORCID, Castro Luís S.ORCID, Faria AldaraORCID, Figueira AlbertoORCID, Sousa MauroORCID, Rodrigues PedroORCID, Roquette RodrigoORCID, Ribeiro RicardoORCID, Cardoso PauloORCID, Domingues JoanaORCID, Manso Maria IsabelORCID, Pereira RuteORCID, Revez TatianaORCID, Dumbrava Bogdan D.ORCID, Turcu Florin, Hutopila Ionut, Banescu Bogdana, Filip Gerald, Copaescu CatalinORCID, Alba Valmorisco MarcosORCID, Manzano Martín IsabelORCID, Martín García de Arboleya Rocio, Ortega Seda JoséORCID, Rodríguez González PabloORCID, Becerra Toro Jose AntonioORCID, Rodríguez Lara EnriqueORCID, González Minchón Jose AntonioORCID, Segura-Sampedro Juan JoséORCID, Jerí-McFarlane SebastiánORCID, Gil-Catalán AlejandroORCID, Craus-Miguel AndreaORCID, Fernández-Vega LauraORCID, González-Argenté XavierORCID, Estaire-Gómez MercedesORCID, Camacho Fernández-Pacheco BorjaORCID, Vitón-Herrero RebecaORCID, Jimenez-Higuera ElisaORCID, Barbero AlejandroORCID, Valverde José M.ORCID, Colás-Ruiz EnriqueORCID, Escales-Oliver Maria del MarORCID, Claramonte-Bellmunt OlgaORCID, Castro-Suárez MartaORCID, Pagés-Valle NailaORCID, Cifuentes-Ródenas José AndrésORCID, Merayo Alvarez Marta, Michi Campos Jose Luis, García González Luis Alejandro, Carrasco Aguilera Beatriz, Iturbe Menéndez Jaime, Rodicio Miravalles Jose Luis, Rodríguez Haro CarmenORCID, Núñez O’Sullivan SaraORCID, García Virosta MarianaORCID, Hernández O’Reilly MaríaORCID, Balciscueta-Coltell IzaskunORCID, Lorenzo-Perez JavierORCID, Martinez-Alcaide SoniaORCID, Martinez-Ramos SusanaORCID, Sebastian-Fuertes MariaORCID, Gomez-Romer LauraORCID, Pelloni Maria M.ORCID, Rahy-Martín Aida CristinaORCID, Yepes-Cano Andrés FelipeORCID, Reguera-Rosal JulioORCID, Lopez-Ruiz Jose A.ORCID, Marenco BeatrizORCID, Retamar-Gentil MarinaORCID, Romero-Vargas EstelaORCID, Gil-Olarte AngelesORCID, Landaluce-Olavarria AitorORCID, Estraviz-Mateos BegoñaORCID, De Francisco-Rios Jose MarioORCID, Sainz-Lete AitorORCID, Emaldi-Abasolo AneORCID, Leon-Valarezo ManoloORCID, Lopes Moreira Claudia C.ORCID, Lizarazu Perez AintzaneORCID, Rodriguez Gonzalez AraceliORCID, Augusto Ponce IñigoORCID, Goena Iglesias Ignacio MariaORCID, González-Prado CristinaORCID, Cabriada GuillermoORCID, López BeatrizORCID, Otero Michelle C.ORCID, Muñoz-Plaza NereaORCID, Palomo AlbertoORCID, Mendoza-Moreno FernandoORCID, Díez-Alonso ManuelORCID, García-Moreno-Nisa FranciscaORCID, Matías-García BelénORCID, Ovejero-Merino EnriqueORCID, Quiroga-Valcárcel AnaORCID, Sánchez-Guillén LuisORCID, Oller-Navarro InmaculadaORCID, Soler-Silva ÁlvaroORCID, Sanchís-López Antonio FranciscoORCID, Blanco-Antona FranciscoORCID, Muñoz-Bellvis LuisORCID, López-Sánchez JaimeORCID, Garrosa-Muñoz SonsolesORCID, Barón-Salvador BeatrizORCID, Nieto-Arranz Juan ManuelORCID, Campos-Serra AndreaORCID, Gràcia-Roman RaquelORCID, Muñoz-Campaña AnnaORCID, Zerpa-Martin Carla, Torrecilla-Portoles AndreaORCID, Landa TessaORCID, Durán Muñoz-Cruzado VirginiaORCID, Pareja-Ciuró FelipeORCID, Aparicio-Sánchez DanielORCID, Perea del Pozo EduardoORCID, Dios-Barbeito SandraORCID, García-Sánchez CarlosORCID, García-Moriana Antonio JesúsORCID, Turrado-Rodriguez VictorORCID, Termes-Serra RoserORCID, Gonzalez-Atienza PaulaORCID, Morales-Sevillano XavierORCID, Torroella AlbaORCID, Ginestà CésarORCID, Escartín AlfredoORCID, Gomez FerneyORCID, Pinillos AnaORCID, Ortega JaumeORCID, Lopez GuillermoORCID, Gutierrez EricORCID, Membrilla-Fernandez Estela, Ocho-Segarra Francisco, González-Castillo Ana María, Pelegrina-Manzano Amalia, Guzmán-Ahumada Juan, Sancho-Insenser Juan Jose, García-Jiménez María Lourdes, Castro-Diez Laura, González-Bermúdez Manuel, Torres-Díaz Mónica, Madarro Pena Carla, Blanco Rodríguez Angélica, Trivedi DhanishaORCID, Reda SouheilORCID, Edvardsson HansORCID, Strömmer LovisaORCID, Caragounis Eva-CorinaORCID, Sillén KarinORCID, Warfvinge Sofia, Bergstedt Fredrik, Enström Philip, Olsson Harald, Rosemar Anders, Young NathalieORCID, Popowicz AgnieszkaORCID, Lerström Johanna, Jäderbo JohannaORCID, Hammarqvist FolkeORCID, Zacharias HannaORCID, Wikström Maria B.ORCID, Stene Hurtsén AnnaORCID, Bayadsi HaythamORCID, Jansson EmmaORCID, Brunstrom NilsORCID, Malers Ellen B.ORCID, Loftås Per I.ORCID, Möller AndersORCID, Atanasova Elena, Zwicky Simone N.ORCID, Schnüriger BeatORCID, Rutka OlgaORCID, Kattakayam Arjun T.ORCID, Alam MushfiqueORCID, Taylor John V.ORCID, Mihailescu AndreiORCID, Karip Eszter T.ORCID, Zeb EhtishamORCID, O’Connor AdamORCID, Pokusevski GoranORCID, Khan MansoorORCID, Florance Charlotte, Swaminathan Christie, Jaunoo Shameen, Sajid Mohammed, Duffy Caoimhe C.ORCID, Rees JohnORCID, Seamon Mark J.ORCID, Martin Niels D.ORCID, McCurry Ian J.ORCID, Vail Emily A.ORCID, Bormann Bradford C.ORCID, Cullinane Daniel C.ORCID, Sawhney Jaswin S.ORCID, Dreifus Jonathan, Sheppard Forest R.ORCID, Coimbra RaulORCID, Albini PaulORCID, Edwards Sara,
Abstract
Abstract
Introduction
Acute appendicitis is a common surgical emergency, and the standard approach to diagnosis and management has been codified in several practice guidelines. Adherence to these guidelines provides insight into independent surgical practice patterns and institutional resource constraints as impediments to best practice. We explored data from the recent ESTES SnapAppy observational cohort study to determine guideline compliance in contemporary practice to identify opportunities to close evidence-to-practice gaps.
Methods
We undertook a preplanned analysis of the ESTES SnapAppy observational cohort study, identifying, at a patient level, congruence with, or deviation from WSES Jerusalem guidelines for the diagnosis and management of acute appendicitis and the Surviving Sepsis Campaign in our cohort. Compliance was then correlated with the incidence of postoperative complications.
Results
Four thousand six hundred and thirteen (4613) consecutive adult and adolescent patients with acute appendicitis were followed from date of admission (November 1, 2020, and May 28, 2021) for 90 days. Patient-level compliance with guideline elements allowed patients to be grouped into those with full compliance (all 5 elements: 13%), partial compliance (1–4 elements: 87%) or noncompliance (0 elements: 0.2%). We identified an excess postoperative complication rate in patients who received noncompliant and partially compliant care, compared with those who received fully guideline-compliant care (36% and 16%, versus 7.3%, p < 0.001).
Conclusions
The observed diagnostic and treatment practices of the participating institutions displayed variability in compliance with key recommendations from existing guidelines. In general, practice was congruent with recommendations for preoperative antibiotic surgical site infection prophylaxis administration, time to surgery, and operative approach. However, there remains opportunities for improvement in the choice of diagnostic imaging modality, postoperative antibiotic stewardship to timely discontinue prophylactic antibiotics, and the implementation of ambulatory treatment pathways for uncomplicated appendicitis in the healthy young adult.
Publisher
Springer Science and Business Media LLC
Subject
Critical Care and Intensive Care Medicine,Orthopedics and Sports Medicine,Emergency Medicine,Surgery
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