Effects of the oxazolidinedione anticonvulsants trimethadione and dimethadione and the barbiturate homolog 5,5-dimethylbarbituric acid onN-nitrosodiethylamine-initiated renal and hepatic carcinogenesis in the F344/NCr rat-Reference-Cited by-同舟云学术

Effects of the oxazolidinedione anticonvulsants trimethadione and dimethadione and the barbiturate homolog 5,5-dimethylbarbituric acid onN-nitrosodiethylamine-initiated renal and hepatic carcinogenesis in the F344/NCr rat

Published:1992-07 Issue:6 Volume:66 Page:413-422
ISSN:0340-5761
Container-title:Archives of Toxicology
language:en
Short-container-title:Arch Toxicol

Author:

Diwan Bhalchandra A.,Nims Raymond W.,Henneman John R.,Ward Jerrold M.,Lubet Ronald A.,Rice Jerry M.

Publisher

Springer Science and Business Media LLC

Subject

Health, Toxicology and Mutagenesis,Toxicology,General Medicine

Link

http://link.springer.com/content/pdf/10.1007/BF02035132.pdf

Reference45 articles.

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3. Brouillette WJ, Brown GB, DeLorey TM, Shirali SS, Grunewald GL (1988) Anticonvulsant activities of phenyl-substituted bicyclic 2,4-oxazolidinediones and monocyclic models. Comparison with binding to the neuronal voltage-dependent sodium channel. J Med Chem 31: 2218–2221

4. Butler TC, Waddell WJ, Poole DT (1965) Demethylation of trimethadione and metharbital by rat liver microsomal enzymes: substrate concentration-yield relationships and competition between substrates. Biochem Pharmacol 14: 937–942

5. Campbell HA, Xu Y-D, Hanigan MH, Pitot HC (1986) Application of quantitative stereology to the evaluation of phenotypically heterogenous enzyme-altered foci in the rat liver. J Natl Cancer Inst 76: 751–767

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