Anti-inflammatory and antifibrotic effects of CBP/β-catenin inhibitor for hepatocytes: small molecular inhibitor, OP-724 possibly improves liver function
Author:
Publisher
Springer Science and Business Media LLC
Subject
Molecular Biology,General Medicine,Pathology and Forensic Medicine
Link
https://link.springer.com/content/pdf/10.1007/s00795-022-00343-8.pdf
Reference41 articles.
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3. Kahn M (2014) Can we safely target the WNT pathway? Nat Rev Drug Discov 13:513–532
4. Teo JL, Ma H, Nguyen C, Lam C, Kahn M (2005) Specific inhibition of CBP/beta-catenin interaction rescues defects in neuronal differentiation caused by a presenilin-1 mutation. Proc Natl Acad Sci U S A 102:12171–12176
5. Henderson WR Jr, Chi EY, Ye X, Nguyen C, Tien YT, Zhou B, Borok Z, Knight DA, Kahn M (2010) Inhibition of Wnt/beta-catenin/CREB binding protein (CBP) signaling reverses pulmonary fibrosis. Proc Natl Acad Sci U S A 107:14309–14314
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