The complete synthesis of favipiravir from 2-aminopyrazine

Author:

Guo Qi,Xu Mingshuo,Guo Shuang,Zhu Fuqiang,Xie Yuanchao,Shen Jingshan

Funder

National Natural Science Foundation of China

Publisher

Springer Science and Business Media LLC

Subject

Materials Chemistry,Industrial and Manufacturing Engineering,General Chemical Engineering,Biochemistry,General Chemistry

Reference24 articles.

1. Bai CQ, Mu JS, Kargbo D, Song YB, Niu WK, Nie WM, Kanu A, Liu WW, Wang YP, Dafae F, Yan T, Hu Y, Deng YQ, Lu HJ, Yang F, Zhang XG, Sun Y, Cao YX, Su HX, Sun Y, Liu WS, Wang CY, Qian J, Liu L, Wang H, Tong YG, Liu ZY, Chen YS, Wang HQ, Kargbo B, Gao GF, Jiang JF (2016) Clinical and virological characteristics of Ebola virus disease patients treated with favipiravir (T-705)-Sierra leone, 2014. Clin Infect Dis 6310:1288–1294. https://doi.org/10.1093/cid/ciw571

2. Beldar SV, Jordis U (2009) Synthetic studies towards the antiviral pyrazine derivative T-705. Institute of Applied Synthetic Chemistry, Vienna University of Technology, Vienna, p 13

3. Cai L, Pike V W, Innis R B (2007) (Aminophenyl)imidazo[1,2-a]pyridine derivatives useful as beta-amyloid PET imaging agents and their preparation. WO2007124345A2 (issued November 1, 2007)

4. El-Nahas A, Hirao K (1999) A theoretical study on 2-hydroxypyrazine and 2,3-dihydroxypyrazine: tautomerism, intramolecular hydrogen bond, solvent effects. J Mol Struct 4591:229–237. https://doi.org/10.1016/s0166-1280(98)00270-x

5. Furuta Y, Egawa H (2000) Nitrogenous heterocyclic carboxamide derivatives or salts thereof and antiviral agents containing both. European Patent Office WO, 00/10569 (issued March 2, 2000)

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