Traditional Eastern European diet and mortality: prospective evidence from the HAPIEE study

Author:

Stefler DenesORCID,Brett Daniel,Sarkadi-Nagy Eszter,Kopczynska Ewa,Detchev Stefan,Bati Aniko,Scrob Mircea,Koenker Diane,Aleksov Bojan,Douarin Elodie,Simonova Galina,Malyutina Sofia,Kubinova Ruzena,Pajak Andrzej,Ruiz Milagros,Peasey Anne,Pikhart Hynek,Bobak Martin

Abstract

Abstract Purpose Cardiovascular disease (CVD) and cancer mortality rates in Eastern Europe are among the highest in the world. Although diet is an important risk factor, traditional eating habits in this region have not yet been explored. This analysis assessed the relationship between traditional dietary pattern and mortality from all-causes, CVD and cancer in Eastern European cohorts. Methods Data from the Health, Alcohol and Psychosocial factors in Eastern Europe prospective cohort were used, including participants from Russia, Poland and the Czech Republic. Based on food frequency questionnaire data, we constructed an Eastern European diet score (EEDS) from nine food groups which can be considered as traditional in this region. The relationship between categorical (low, moderate, high) and continuous (range 0–18) EEDS and mortality was estimated with Cox-regression. Results From 18,852 eligible participants, 2234 died during follow-up. In multivariable adjusted models, participants with high adherence to the traditional Eastern European diet had significantly higher risk of all-cause (HR 1.23; 95% CI 1.08–1.42) and CVD (1.34; 1.08–1.66) deaths compared to those with low adherence. The association with cancer mortality was only significant in Poland (high vs. low EEDS: 1.41; 1.00–1.98). From the specific EEDS components, high consumption of lard was significantly positively related to all three mortality outcomes, while preserved fruit and vegetable consumption showed consistent inverse associations. Conclusion Our results suggest that traditional eating habits may contribute to the poor health status, particularly the high CVD mortality rates, of populations in Eastern Europe. Adequate public health nutritional interventions in this region are essential.

Funder

Wellcome Trust

National Institute of Aging

MacArthur Foundation Initiative on Social Upheaval and Health

UCL Grand Challenges Small Grant

Horizon 2020 Research and Innovation Programme

Russian Scientific Foundation

Russian Academy of Science

Publisher

Springer Science and Business Media LLC

Subject

Nutrition and Dietetics,Medicine (miscellaneous)

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