Author:
Dakhakhni Tahani H.,Alsufyani Daniah
Abstract
AbstractThis study utilized the FTIR technique to investigate and assess the herbicide 2, 4-Dichlorophenoxyacetic acid-induced blood serum toxicity. The study was conducted on 15 albino Wistar rats, divided into two groups: a control group (5 rats) and an intoxicated group (10 rats). Serum samples were investigated using the FTIR technique, and the obtained spectra from both groups were analyzed. Our results indicated a reduction in glucose, lipid, and protein content and remarkable changes in the secondary structure of protein in response to herbicide toxicity. A rise in the DNA content was also noticed. Our findings prove the FTIR technique's capability to detect biochemical changes in biological samples due to toxicity.
Funder
King Abdulaziz City for Science and Technology;
Publisher
Springer Science and Business Media LLC
Subject
General Earth and Planetary Sciences,General Physics and Astronomy,General Engineering,General Environmental Science,General Materials Science,General Chemical Engineering