Radical Hysterectomy After the LACC Trial: Back to Radical Vaginal Surgery

Author:

Querleu Denis,Hudry Delphine,Narducci Fabrice,Rychlik AgnieszkaORCID

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Oncology

Reference75 articles.

1. Ramirez PT, Frumovitz M, Pareja R, et al. Minimally invasive versus abdominal radical hysterectomy for cervical cancer. N Engl J Med. 2018;379:1895–904 Randomized phase III trial that showed benefit of open radical hysterectomy over minimally invasive aproach in early stage cervical cancer.

2. Querleu D, Cibula D, Concin N, et al. Laparoscopic radical hysterectomy: a European Society of Gynaecological Oncology (ESGO) statement. Int J Gynecol Cancer. 2020;30:15.

3. Koh WJ, Abu-Rustum NR, Bean S, et al. Cervical cancer, Version 3.2019, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2019;17:64–84.

4. Chiva L, Zanagnolo V, Querleu D, et al. SUCCOR study: an international European cohort observational study comparing minimallyly invasive surgery versus open abdominal radical hysterectomy in patients with stage IB1 cervical cancer. Int J Gynecol Cancer. 2020;30:1269–77 Observational retrospective study that collected data from 89 European centres. The authors reported more oncological risk related to minimally invasive surgery in early stage cervical cancer. However, the results were not confirmed in patients with tumors smaller than 2 cm, after cone biopsy, when uterine manipulator was not used and when protective maneuvers were performed.

5. Naumann RW. Minimally invasive radical hysterectomy has many benefits compared with open radical hysterectomy: will the LACC trial cause the premature demise of this procedure? J Minim Invasive Gynecol. 2019;26:379–80.

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