Treatment of poems syndrome

Author:

Dispenzieri Angela,Gertz Morie A.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Oncology

Reference46 articles.

1. Bardwick PA, Zvaifler NJ, Gill GN, et al.: Plasma cell dyscrasia with polyneuropathy, organomegaly, endocrinopathy, M protein, and skin changes: the POEMS syndrome. Report on two cases and a review of the literature. Medicine 1980, 59:311–322. Authors introduce two new cases and review the literature, but devise the acronym POEMS to refer to the syndrome.

2. Nakanishi T, Sobue I, Toyokura Y, et al.: The Crow-Fukase syndrome: a study of 102 cases in Japan. Neurology 1984, 34:712–720. The largest English language report of the syndrome from Japan (102 patients from a nationwide survey and review of the Japanese literature). The paper emphasizes that the syndrome may exist in the absence of bone lesions, may be associated with Castleman disease, and monoclonal kappa plasma cell clones are rare.

3. Driedger H, Pruzanski W: Plasma cell neoplasia with peripheral polyneuropathy. A study of five cases and a review of the literature. Medicine 1980, 59:301–310.

4. Soubrier MJ, Dubost JJ, Sauvezie BJ: POEMS syndrome: a study of 25 cases and a review of the literature. French Study Group on POEMS Syndrome. Am J Med 1994, 97:543–553. A report of 25 patients from France with an extensive review of the literature incorporating 114 non-Asian cases derived from 76 reports, in addition to the 102 cases in Japan reported by Nakanishi et al. [2•].

5. Dispenzieri A, Kyle RA, Lacy MQ, et al.: POEMS syndrome: definitions and long-term outcome. Blood 2003, 101:2496–2506. This paper involves the largest series (99 patients) from a single institution. It sets forth diagnostic criteria for the diagnosis. The paper emphasizes that the long-term outcome for patients is good, the number of POEMS features is not prognostic, patients can acquire additional features over time, and pulmonary hypertension and congestive heart failure may be part of the syndrome. The authors demonstrate that fingernail clubbing and extravascular volume overload are the presenting features most predictive of survival.

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