Immunotherapy in HPV-Related Oropharyngeal Cancers
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Oncology
Link
https://link.springer.com/content/pdf/10.1007/s11864-023-01050-x.pdf
Reference38 articles.
1. Chaturvedi AK, Engels EA, Pfeiffer RM, Hernandez BY, Xiao W, Kim E, et al. Human papillomavirus and rising oropharyngeal cancer incidence in the United States. J Clin Oncol : Official J Ame Soc Clin Oncol. 2011;29(32):4294–301.
2. Ang KK, Harris J, Wheeler R, Weber R, Rosenthal DI, Nguyen-Tân PF, et al. Human papillomavirus and survival of patients with oropharyngeal cancer. New England J Med. 2010;363(1):24–35.
3. Ferris RL, Blumenschein G Jr, Fayette J, Guigay J, Colevas AD, Licitra L, et al. Nivolumab for recurrent squamous-cell carcinoma of the head and neck. New England J Med. 2016;375(19):1856–67.
4. • Cohen EEW, Soulières D, Le Tourneau C, Dinis J, Licitra L, Ahn MJ, et al. Pembrolizumab versus methotrexate, docetaxel, or cetuximab for recurrent or metastatic head-and-neck squamous cell carcinoma (KEYNOTE-040): a randomised, open-label, phase 3 study. Lancet (London, England). 2019;393(10167):156–67 This article is of importance because it is a phase III study showing the OS benefit of pembrolizumab monotherapy in patients with recurrent or metastatic HNSCC.
5. • Burtness B, Harrington KJ, Greil R, Soulières D, Tahara M, de Castro G Jr, et al. Pembrolizumab alone or with chemotherapy versus cetuximab with chemotherapy for recurrent or metastatic squamous cell carcinoma of the head and neck (KEYNOTE-048): a randomised, open-label, phase 3 study. Lancet (London, England). 2019;394(10212):1915–28 This article is of importance because it is a phase III study establishing pembrolizumab plus platinum/5FU as a first-line treatment for recurrent or metastatic HNSCC and pembrolizumab monotherapy as a first-line option for patients with PD-L1 positive disease.
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2. Human Papillomavirus-Induced Chromosomal Instability and Aneuploidy in Squamous Cell Cancers;Viruses;2024-03-25
3. Molecular aspects of cervical cancer: a pathogenesis update;Frontiers in Oncology;2024-03-19
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