Molecular Diagnosis of the Tissue of Origin in Cancer of Unknown Primary Site: Useful in Patient Management-Reference-Cited by-同舟云学术

Molecular Diagnosis of the Tissue of Origin in Cancer of Unknown Primary Site: Useful in Patient Management

Published:2013-08-29 Issue:4 Volume:14 Page:634-642
ISSN:1527-2729
Container-title:Current Treatment Options in Oncology
language:en
Short-container-title:Curr. Treat. Options in Oncol.

Author:

Greco F. Anthony

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Oncology

Link

http://link.springer.com/content/pdf/10.1007/s11864-013-0257-1.pdf

Reference31 articles.

1. Greco FA, Hainsworth JD. Cancer of unknown primary site. In: Devita VT, Lawrence TS, Rosenberg SA, editors. Cancer: principles and practice of oncology. 9th ed. Philadelphia: Lippincott, Williams & Wilkins; 2011. p. 2033–51. This is a comprehensive review covering all the known aspects of the clinicopathologic syndrome of cancer of unknown primary site.

2. Oien KA. Pathologic evaluation of unknown primary cancer. Semin Oncol. 2009;36:8–37.

3. Greco FA, Erlander MG. Molecular classification of cancer of unknown primary site. Mol Diagn Ther. 2009;13:367–73.

4. Greco FA, Spigel DR, Yardley DA, et al. Molecular profiling in unknown primary cancer: accuracy of tissue of origin prediction. Oncol. 2010;15:500–6. This study compared the molecular assay diagnosis to the actual primary site that was found months to years later in patients who initially presented with CUP. These CUP patients who developed latent primaries provide a “gold standard” to test the accuracy of molecular profiling assay.

5. Kerr SE, Schnabel CA, Sullivan PS, et al. Multisite validation study to determine performance characteristics of a 92-gene molecular cancer classifier. Clin Cancer Res. 2012;18:3953–60.

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