The Role of Induction Therapy for Sinonasal Cancers

Author:

Kong Keonho A.,Thorp Brian D.,Sheth Siddharth H.ORCID

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Oncology

Reference32 articles.

1. Turner JH, Reh DD. Incidence and survival in patients with sinonasal cancer: a historical analysis of population-based data. Head Neck. 2012;34:877–85.

2. Sanghvi S, Khan MN, Patel NR, Yeldandi S, Baredes S, Eloy JA. Epidemiology of sinonasal squamous cell carcinoma: a comprehensive analysis of 4994 patients. Laryngoscope. 2014;124(1):76–83. https://doi.org/10.1002/lary.24264.

3. Ansa B, Goodman M, Ward K, Kono SA, Owonikoko TK, Higgins K, Beitler JJ, Grist W, Wadsworth T, el-Deiry M, Chen AY, Khuri FR, Shin DM, Saba NF. Paranasal sinus squamous cell carcinoma incidence and survival based on Surveillance, Epidemiology, and End Results data, 1973 to 2009. Cancer. 2013;119(14):2602–10. https://doi.org/10.1002/cncr.28108.

4. •• Abdelmeguid AS, Teeramatwanich W, Roberts DB, et al. Neoadjuvant chemotherapy for locoregionally advanced squamous cell carcinoma of the paranasal sinuses. Cancer. 2021;127(11):1788–95. https://doi.org/10.1002/cncr.33452. This is the largest retrospective study available in recent literature for role of IC in SNSCC. It showed improved survival outcomes in patients with at least stable disease in response to IC. Also it showed that there was no significant difference in outcomes between post-IC treatment modality. It also showed an improvement in orbital preservation rates with IC

5. • Murr AT, Lenze NR, Weiss JM, et al. Sinonasal squamous cell carcinoma survival outcomes following induction chemotherapy vs standard of care therapy. Otolaryngol Head Neck Surg: official journal of american academy of otolaryngology-head and neck surgery. 2022;167:846–51. https://doi.org/10.1177/01945998221083097. This study showed improvement in 3-year OS with IC compared to current standard of care through 1:1 matched analysis

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