Pharmacological Properties of Phosphatidylserine in the Aging Brain: Biochemical Aspects and Therapeutic Potential

Author:

Calderini G.,Bellini F.,Bonetti A. C.,Galbiati E.,Rubini R.,Zanotti A.,Toffano G.

Publisher

Springer New York

Reference33 articles.

1. Aporti F, Nelsen JM, Goldstein L (1982) A quantitative EEG study at cortical and subcortical levels of the effects of brain cortical phosphatidylserine (BC-PS) in rats, and of its interaction with scopolamine. Res Commun Psychol Psychiat Behav 7: 131–143.

2. Aporti F, Borsato R, Calderini G, Rubini R, Toffano G, Zanotti A, Valzelli L, Goldstein L (1986) Age-dependent spontaneous EEG bursts in rats: effect of brain phosphatidylserine. Neurobiol Aging, 7(2): 115–120.

3. Bartus RT, Dean RL III, Beer B, Lippa AS (1982) The cholinergic hypothesis of geriatric memory dysfunction. Science 217: 408–416.

4. Bigon L, Boarato E, Bruni A, Leon A, Toffano G (1979) Pharmacological effects of phosphatidylserine liposomes: regulation of glycolysis and energy level in brain. Br J Pharmacol 66: 167–174.

5. Bonetti AC, Bellini F, Calderini G, Galbiati E, Toffano G (1985) Age-dependent changes in the molecular mechanisms controlling prolactin secretion in aged male rats: effect of a treatment with phosphatidylserine. Endocrinology, submitted.

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