Selective Cyclooxygenase-2 Inhibitors as Potential Therapeutic Agents for Inflammatory Diseases

Author:

Chan Chi-Chung,Rodger Ian W.

Publisher

Springer US

Reference20 articles.

1. Brideau, C., Kargman, S., Liu, S., Dallob, A.L., Ehrich, E.W., Rodger, I.W., and Chan, C.-C., 1996, A human whole blood assay for clinical evaluation of biochemical efficacy of cyclooxygenase inhibitors, Inflammation Res., in press.

2. Chan, C.-C., Boyce, S., Brideau, C., Ford-Hutchinson, A.W, Gordon, R., Guay, D., Hill, R., Li, C.-S., Mancini, J., Penneton, M., Prasit, P., Rasori, R., Riendeau, D., Roy, P., Tagari, P., Vickers, P., Wong, E., and Rodger, I.W., 1995a, Pharmacology of a selective cyclooxygenase-2 inhibitor L-745,337: a novel non-steroidal anti-inflammatory agent with an ulcerogenic sparing effect in rat and non-human primate stomach, J. Pharmacol. Exp. Then 274: 1531.

3. Chan, C.-C., DiBattista, J.A., Zhao, J., Pelletier, J.-P., Martel-Pelletier, J., Kennedy, B.P., Brideau, C., and Rodger, I.W., 1995b, Induction of cyclooxygenase-2 (Cox-2) in human articular chondrocytes and inhibition of PGE2 synthesis by a selective Cox-2 inhibitor, Inflammation Res., 44 (Suppl. 3): S275.

4. DeWitt, D.L., and Smith, W.L., 1988, Primary structure of prostaglandin G/H synthase from sheep vesicular gland determined from the complementary DNA sequence, Proc. Natl. Acad. Sci. 85: 1412.

5. DeWitt, D.L., El-harith, E.A., Kraemer, S.A., Andrews, M.J., Yao, E.F., Armstrong, R.L., and Smith W.L., 1990, The aspirin and heme-binding sites of ovine and murine prostaglandin endoperoxide synthase, J. Biol. Chem. 265: 5192.

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