Sensitivity of HCN channel deactivation to cAMP is amplified by an S4 mutation combined with activation mode shift-Reference-Cited by-同舟云学术

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Sensitivity of HCN channel deactivation to cAMP is amplified by an S4 mutation combined with activation mode shift

Published:2009-06-21 Issue:5 Volume:458 Page:877-889
ISSN:0031-6768
Container-title:Pflügers Archiv - European Journal of Physiology
language:en
Short-container-title:Pflugers Arch - Eur J Physiol

Author:

Wicks Nadine L.,Chan Kerry S. C.,Madden Zarina,Santoro Bina,Young Edgar C.

Publisher

Springer Science and Business Media LLC

Subject

Physiology (medical),Clinical Biochemistry,Physiology

Link

http://link.springer.com/content/pdf/10.1007/s00424-009-0687-6.pdf

Reference52 articles.

1. Altomare C, Bucchi A, Camatini E, Baruscotti M, Viscomi C, Moroni A, DiFrancesco D (2001) Integrated allosteric model of voltage gating of HCN channels. J Gen Physiol 117:519–532

2. Barbuti A, DiFrancesco D (2008) Control of cardiac rate by “funny” channels in health and disease. Ann N Y Acad Sci 1123:213–223

3. Bell DC, Yao H, Saenger RC, Riley JH, Siegelbaum SA (2004) Changes in local S4 environment provide a voltage-sensing mechanism for mammalian hyperpolarization-activated HCN channels. J Gen Physiol 123:5–19

4. Bezanilla F, Perozo E, Papazian DM, Stefani E (1991) Molecular basis of gating charge immobilization in Shaker potassium channels. Science 254:679–683

5. Brown HF, DiFrancesco D, Noble SJ (1979) How does adrenaline accelerate the heart? Nature 280:235–236

Cited by 12 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Subunit-specific conductance of single HCN pacemaker channels at femtosiemens resolution;2024-09-03

2. A195V mutation identified in sudden cardiac death decreases membrane localization and activation current density and abolishes cAMP sensitivity of HCN4 channels;2023-03-16

3. The HCN domain is required for HCN channel cell-surface expression and couples voltage- and cAMP-dependent gating mechanisms;Journal of Biological Chemistry;2020-06

4. Cytoplasmic Autoinhibition in HCN Channels is Regulated by the Transmembrane Region;The Journal of Membrane Biology;2020-03-07

5. HCN domain is required for HCN channel expression and couples voltage- and cAMP-dependent gating mechanisms;2020-03-02

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