The bundle crossing region is responsible for the inwardly rectifying internal spermine block of the Kir2.1 channel
Author:
Publisher
Springer Science and Business Media LLC
Subject
Physiology (medical),Clinical Biochemistry,Physiology
Link
http://link.springer.com/content/pdf/10.1007/s00424-013-1322-0.pdf
Reference73 articles.
1. Bichet D, Haass FA, Jan LY (2003) Merging functional studies with structures of inward-rectifier K+ channels. Nat Rev Neurosci 4(12):957–967. doi: 10.1038/nrn1244
2. Chang HR, Kuo CC (2007) Characterization of the gating conformational changes in the felbamate binding site in NMDA channels. Biophys J 93(2):456–466
3. Chang HR, Kuo CC (2007) Extracellular proton-modulated pore-blocking effect of the anticonvulsant felbamate on NMDA channels. Biophys J 93(6):1981–1992
4. Chang HK, Yeh SH, Shieh RC (2003) The effects of spermine on the accessibility of residues in the M2 segment of Kir2.1 channels expressed in Xenopus oocytes. J Physiol 553(Pt 1):101–112. doi: 10.1113/jphysiol.2003.052845
5. Chang HK, Yeh SH, Shieh RC (2005) A ring of negative charges in the intracellular vestibule of Kir2.1 channel modulates K+ permeation. Biophys J 88(1):243–254
Cited by 8 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Anomalous enhancement of resurgent Na+ currents at high temperatures by SCN9A mutations underlies the episodic heat-enhanced pain in inherited erythromelalgia;Scientific Reports;2019-08-22
2. E224G Regulation of the PIP 2 -Induced Gating Kinetics of Kir2.1 Channels;Chinese Physics Letters;2017-01
3. The Biophysical Basis Underlying Gating Changes in the p.V1316A Mutant Nav1.7 Channel and the Molecular Pathogenesis of Inherited Erythromelalgia;PLOS Biology;2016-09-21
4. A synergistic blocking effect of Mg2+ and spermine on the inward rectifier K+ (Kir2.1) channel pore;Scientific Reports;2016-02-12
5. Intracellular spermine blocks TRPC4 channel via electrostatic interaction with C-terminal negative amino acids;Pflügers Archiv - European Journal of Physiology;2015-12-02
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3