An impurity in phenol red opens an ion channel in cultured human cells
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Developmental Biology,General Medicine,Cell Biology,Clinical Biochemistry,Developmental Biology
Link
http://link.springer.com/content/pdf/10.1007/BF02634154.pdf
Reference13 articles.
1. Bindal, R. D.; Carlson, K. E.; Katzenellenbogen, B. S., et al. Lipophilic impurities, not phenolsulfonphthalein, account for the estrogenic activity in commercial preparations of phenol red. J. Steroid Biochem. 31:287–293; 1988.
2. Bindal, R. D.; Katzenellenbogen, J. A. Bis (4-hydroxyphenyl)[2-(phenoxysulfonyl) phenyl]methane: isolation and structure elucidation of a novel estrogen from commercial preparations of phenol red (phenolsulfonphthalein). J. Med. Chem. 31:1978–1983; 1988.
3. Dall’Asta, V.; Gazzola, G. C.; Longo, N., et al. Perturbation of Na+ and K+ gradients in human fibroblasts incubated in unsupplemented saline solutions. Biochim. Biophys. Acta 860:1–8; 1986.
4. Dall’Asta, V.; Rebecchi, F.; Longo, N., et al. Serum-dependent changes of intracellular Na+ and K+ concentrations in cultured human fibroblasts. Cell. Biol. Int. Rep. 10:156; 1986.
5. Grady, L. H.; Nonneman, D. J.; Rottinghaus, G. E., et al. pH-dependent cytotoxicity of contaminants of phenol red for MCF-7 breast cancer cells. Endocrinology 129:3321–3330; 1991.
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