Screening for pancreatic cancer in high-risk individuals using MRI: optimization of scan techniques to detect small lesions
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Published:2024-05-11
Issue:3
Volume:23
Page:295-308
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ISSN:1389-9600
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Container-title:Familial Cancer
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language:en
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Short-container-title:Familial Cancer
Author:
Boekestijn Bas,Feshtali Shirin,Vasen Hans,van Leerdam Monique E.,Bonsing Bert A.,Mieog J. Sven D.,Wasser Martin N.
Abstract
AbstractPancreatic cancer has a dismal prognosis in the general population. However, early detection and treatment of disease in high-risk individuals can improve survival, as patients with localized disease and especially patients with lesions smaller than 10 mm show greatly improved 5-year survival rates. To achieve early detection through MRI surveillance programs, optimization of imaging is required. Advances in MRI technologies in both hardware and software over the years have enabled reliable detection of pancreatic cancer at a small size and early stage. Standardization of dedicated imaging protocols for the pancreas are still lacking. In this review we discuss state of the art scan techniques, sequences, reduction of artifacts and imaging strategies that enable early detection of lesions. Furthermore, we present the imaging features of small pancreatic cancers from a large cohort of high-risk individuals. Refinement of MRI techniques, increased scan quality and the use of artificial intelligence may further improve early detection and the prognosis of pancreatic cancer in a screening setting.
Publisher
Springer Science and Business Media LLC
Reference49 articles.
1. Cancer of the Pancreas - Cancer Stat Facts. In: SEER. https://seer.cancer.gov/statfacts/html/pancreas.html. Accessed 26 Jul 2023 2. Vasen H, Ibrahim I, Ponce CG, Slater EP, Matthäi E, Carrato A, Earl J, Robbers K, van Mil AM, Potjer T, Bonsing BA, de Cappel VTN, Bergman WH, Wasser W, Morreau M, Klöppel H, Schicker G, Steinkamp C, Figiel M, Esposito J, Mocci I, Vazquez-Sequeiros E, Sanjuanbenito E, Muñoz-Beltran A, Montans M, Langer J, Fendrich P, Bartsch V DK (2016) Benefit of Surveillance for Pancreatic Cancer in High-Risk individuals: Outcome of Long-Term Prospective Follow-Up Studies From Three European Expert centers. J Clin Oncol Off J Am Soc Clin Oncol 34:2010–2019. https://doi.org/10.1200/JCO.2015.64.0730 3. Canto MI, Almario JA, Schulick RD, Yeo CJ, Klein A, Blackford A, Shin EJ, Sanyal A, Yenokyan G, Lennon AM, Kamel IR, Fishman EK, Wolfgang C, Weiss M, Hruban RH, Goggins M (2018) Risk of neoplastic progression in individuals at high risk for pancreatic Cancer Undergoing Long-Term Surveillance. Gastroenterology 155:740–751e2. https://doi.org/10.1053/j.gastro.2018.05.035 4. Klatte DCF, Boekestijn B, Wasser MNJM, Feshtali Shahbazi S, Ibrahim IS, Mieog JSD, Luelmo SAC, Morreau H, Potjer TP, Inderson A, Boonstra JJ, Dekker FW, Vasen HFA, van Hooft JE, Bonsing BA, van Leerdam ME (2022) Pancreatic Cancer surveillance in carriers of a germline CDKN2A pathogenic variant: yield and outcomes of a 20-Year prospective Follow-Up. J Clin Oncol 40:3267–3277. https://doi.org/10.1200/JCO.22.00194 5. Dbouk M, Katona BW, Brand RE, Chak A, Syngal S, Farrell JJ, Kastrinos F, Stoffel EM, Blackford AL, Rustgi AK, Dudley B, Lee LS, Chhoda A, Kwon R, Ginsberg GG, Klein AP, Kamel I, Hruban RH, He J, Shin EJ, Lennon AM, Canto MI, Goggins M (2022) The Multicenter Cancer of pancreas Screening Study: Impact on Stage and Survival. J Clin Oncol 40:3257–3266. https://doi.org/10.1200/JCO.22.00298
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