A pilot study investigating feasibility of mainstreaming germline BRCA1 and BRCA2 testing in high-risk patients with breast and/or ovarian cancer in three tertiary Cancer Centres in Ireland-Reference-Cited by-同舟云学术

A pilot study investigating feasibility of mainstreaming germline BRCA1 and BRCA2 testing in high-risk patients with breast and/or ovarian cancer in three tertiary Cancer Centres in Ireland

Published:2022-08-27 Issue:2 Volume:22 Page:135-149
ISSN:1389-9600
Container-title:Familial Cancer
language:en
Short-container-title:Familial Cancer

Author:

McVeigh Terri Patricia^ORCID,Sweeney Karl J.,Brennan Donal J.,McVeigh Una M.,Ward Simon,Strydom Ann,Seal Sheila,Astbury Katherine,Donnellan Paul,Higgins Joanne,Keane Maccon,Kerin Michael J.,Malone Carmel,McGough Pauline,McLaughlin Ray,O’Leary Michael,Rushe Margaret,Barry Michael Kevin,MacGregor Geraldine,Sugrue Michael,Yousif Ala,Al-Azawi Dhafir,Berkeley Eileen,Boyle Terence J.,Connolly Elizabeth M.,Nolan Carmel,Richardson Elaine,Giffney Claire,Doyle Samantha B.,Broderick Sheila,Boyd William,McVey Ruaidhri,Walsh Thomas,Farrell Michael,Gallagher David J.,Rahman Nazneen,George Angela J.

Funder

NIHR Biomedical Research Centre, Royal Marsden NHS Foundation Trust/Institute of Cancer Research

Health Research Board

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Genetics (clinical),Oncology,Genetics

Link

https://link.springer.com/content/pdf/10.1007/s10689-022-00313-0.pdf

Reference90 articles.

1. Witjes VM, van Bommel MHD, Ligtenberg MJL, Vos JR, Mourits MJE, Ausems MGEM et al (2022) Probability of detecting germline BRCA1/2 pathogenic variants in histological subtypes of ovarian carcinoma a meta-analysis. Gynecologic Oncol 164(1):221–230

2. Lin J, Sharaf RN, Saganty R, Ahsan D, Feit J, Khoury A et al (2021) Achieving universal genetic assessment for women with ovarian cancer: are we there yet? A systematic review and meta-analysis. Gynecol Oncol 162(2):506–516

3. Buys SS, Sandbach JF, Gammon A, Patel G, Kidd J, Brown KL et al (2017) A study of over 35,000 women with breast cancer tested with a 25-gene panel of hereditary cancer genes. Cancer 123(10):1721–1730

4. Beitsch PD, Whitworth PW, Hughes K, Patel R, Rosen B, Compagnoni G et al (2019) Underdiagnosis of hereditary breast cancer: are genetic testing guidelines a tool or an obstacle? J Clin Oncol 37(6):453–460

5. Copson ER, Maishman TC, Tapper WJ, Cutress RI, Greville-Heygate S, Altman DG et al (2018) Germline BRCA mutation and outcome in young-onset breast cancer (POSH): a prospective cohort study. Lancet Oncol 19(2):169–180

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Psychosocial experiences and outcomes for individuals with breast cancer after mainstream genetic testing;2024-08-22

2. Patients’ experiences with pre-test genetic counseling provided by breast cancer healthcare professionals: Results from a large prospective multicenter study;The Breast;2023-06