The CNS-penetrating taxane drug TPI 287 potentiates antiglioma activity of the AURKA inhibitor alisertib in vivo-Reference-Cited by-同舟云学术

The CNS-penetrating taxane drug TPI 287 potentiates antiglioma activity of the AURKA inhibitor alisertib in vivo

Published:2023-01-25 Issue:2 Volume:91 Page:191-201
ISSN:0344-5704
Container-title:Cancer Chemotherapy and Pharmacology
language:en
Short-container-title:Cancer Chemother Pharmacol

Author:

Sak Müge,Williams Brian J.,Zumbar Cory T.,Teer Landon,Al-Kawaaz Mustafa N. G.,Kakar Aastha,Hey Andrew J.,Wilson Megan J.,Schier Leslie M.,Chen Joseph,Lehman Norman L.^ORCID

Funder

National Institute of Health

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Cancer Research,Pharmacology,Toxicology,Oncology

Link

https://link.springer.com/content/pdf/10.1007/s00280-023-04503-0.pdf

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3. Lehman NL, O’Donnell JP, Whiteley LJ, Stapp RT, Lehman TD, Roszka KM, Schultz LR, Williams CJ, Mikkelsen T, Brown SL, Ecsedy JA, Poisson LM (2012) Aurora A is differentially expressed in gliomas, is associated with patient survival in glioblastoma and is a potential chemotherapeutic target in gliomas. Cell Cycle 11(3):489–502. https://doi.org/10.4161/cc.11.3.18996

4. Qiao W, Guo B, Zhou H, Xu W, Chen Y, Liang Y, Dong B (2017) miR-124 suppresses glioblastoma growth and potentiates chemosensitivity by inhibiting AURKA. Biochem Biophys Res Commun 486(1):43–48. https://doi.org/10.1016/j.bbrc.2017.02.120

5. Asteriti IA, Giubettini M, Lavia P, Guarguaglini G (2011) Aurora-A inactivation causes mitotic spindle pole fragmentation by unbalancing microtubule-generated forces. Mol Cancer 10:131. https://doi.org/10.1186/1476-4598-10-131

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1. Aurora kinase A inhibition plus Tumor Treating Fields suppress glioma cell proliferation in a cilium-independent manner;Translational Oncology;2024-07

2. Phase 1 trial of TPI 287, a microtubule stabilizing agent, in combination with bevacizumab in adults with recurrent glioblastoma;Neuro-Oncology Advances;2024-01-01

3. Aurora Kinase A Inhibition plus Tumor Treating Fields Suppress Glioma Cell Proliferation in a Cilium-Independent Manner;2023-11-30