Novel complementary antitumour effects of celastrol and metformin by targeting IκBκB, apoptosis and NLRP3 inflammasome activation in diethylnitrosamine-induced murine hepatocarcinogenesis-Reference-Cited by-同舟云学术

Novel complementary antitumour effects of celastrol and metformin by targeting IκBκB, apoptosis and NLRP3 inflammasome activation in diethylnitrosamine-induced murine hepatocarcinogenesis

Published:2020-01-27 Issue:2 Volume:85 Page:331-343
ISSN:0344-5704
Container-title:Cancer Chemotherapy and Pharmacology
language:en
Short-container-title:Cancer Chemother Pharmacol

Author:

Saber Sameh^ORCID,Ghanim Amal M. H.,El-Ahwany Eman,El-Kader Eman M. Abd

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Cancer Research,Pharmacology,Toxicology,Oncology

Link

http://link.springer.com/content/pdf/10.1007/s00280-020-04033-z.pdf

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3. Moossavi M, Parsamanesh N, Bahrami A, Atkin SL, Sahebkar A (2018) Role of the NLRP3 inflammasome in cancer. Molecular cancer 17(1):158

4. Saber S, Mahmoud AAA, Goda R, Helal NS, El-ahwany E, Abdelghany RH (2018) Perindopril, fosinopril and losartan inhibited the progression of diethylnitrosamine-induced hepatocellular carcinoma in mice via the inactivation of nuclear transcription factor kappa-B. Toxicol Lett 295:32–40. https://doi.org/10.1016/j.toxlet.2018.05.036

5. Gilmore TD (2006) Introduction to NF-κB: players, pathways, perspectives. Oncogene 25(51):6680

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