Cabozantinib-induced serum creatine kinase elevation and rhabdomyolysis: a retrospective case series

Author:

Yamanaka Taro,Takemura Kohji,Hayashida Michikata,Suyama Koichi,Urakami Shinji,Miura YujiORCID

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Cancer Research,Pharmacology,Toxicology,Oncology

Reference19 articles.

1. Moghadam-Kia S, Oddis CV, Aggarwal R (2016) Approach to asymptomatic creatine kinase elevation. Cleve Clin J Med 83(1):37–42. https://doi.org/10.3949/ccjm.83a.14120

2. Adenis A, Bouche O, Bertucci F, Kalbacher E, Fournier C, Cassier P, Collard O, Bay JO, Italiano A, Chevreau C, Clisant S, Kramar A, Blay JY, Penel N (2012) Serum creatine kinase increase in patients treated with tyrosine kinase inhibitors for solid tumors. Med Oncol 29(4):3003–3008. https://doi.org/10.1007/s12032-012-0204-1

3. Choueiri TK, Escudier B, Powles T, Mainwaring PN, Rini BI, Donskov F, Hammers H, Hutson TE, Lee JL, Peltola K, Roth BJ, Bjarnason GA, Geczi L, Keam B, Maroto P, Heng DY, Schmidinger M, Kantoff PW, Borgman-Hagey A, Hessel C, Scheffold C, Schwab GM, Tannir NM, Motzer RJ, M Investigators (2015) Cabozantinib versus everolimus in advanced renal-cell carcinoma. N Engl J Med 373(19):1814–1823. https://doi.org/10.1056/NEJMoa1510016

4. Choueiri TK, Halabi S, Sanford BL, Hahn O, Michaelson MD, Walsh MK, Feldman DR, Olencki T, Picus J, Small EJ, Dakhil S, George DJ, Morris MJ (2017) Cabozantinib versus sunitinib as initial targeted therapy for patients with metastatic renal cell carcinoma of poor or intermediate risk: the alliance A031203 CABOSUN trial. J Clin Oncol 35(6):591–597. https://doi.org/10.1200/JCO.2016.70.7398

5. Tomita Y, Tatsugami K, Nakaigawa N, Osawa T, Oya M, Kanayama H, Nakayama Kondoh C, Sassa N, Nishimura K, Nozawa M, Masumori N, Miyoshi Y, Kuroda S, Tanaka S, Kimura A, Tamada S (2020) Cabozantinib in advanced renal cell carcinoma: a phase II, open-label, single-arm study of Japanese patients. Int J Urol 27(11):952–959. https://doi.org/10.1111/iju.14329

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