Induction of histone acetylation and inhibition of growth by phenyl alkanoic acids and structurally related molecules

Author:

Lea Michael A.,Shareef Asif,Sura Monali,desBordes Charles

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Cancer Research,Pharmacology,Toxicology,Oncology

Reference29 articles.

1. Boffa LC, Vidali G, Mann RS, Allfrey VG (1978) Suppression of histone deacetylation in vivo and in vitro by sodium butyrate J Biol Chem 253:3364

2. Carducci MA, Nelson JB, Chan-Tack KM, Ayyagari SR, Sweatt WH, Campbell PA, Nelson WG, Simons JW (1996) Phenylbutyrate induces apoptosis in human prostate cancer and is more potent than phenylacetate. Clin Res 2:379

3. Chang T-H, Szabo E (2002) Enhanced growth inhibition by combination differentiation therapy with ligands of peroxisome proliferator-activated receptor-? and inhibitors of histone deacetylase in adenocarcinoma of the lung. Clin Cancer Res 8:1206

4. Clarke KO, Ludeman SM, Springer JB, Colvin OM, Lea MA, Harrison LE, (2002) Exposure to a deuterated analogue of phenylbutyrate retards S phase progression in HT-29 colon cancer cells. J Pharm Sci 91:1054

5. Fajas L, Egler V, Reiter R, Hansen J, Kristiansen K, Debril MB, Miard S, Auwerx J (2002) The retinoblastoma-histone deacetylase 3 complex inhibits PPAR? and adipocyte differentiation. Dev Cell 3:903

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