Ivermectin induces nonprotective autophagy by downregulating PAK1 and apoptosis in lung adenocarcinoma cells

Author:

Li Man-Yuan,Zhang Jiao,Lu Xiao,Zhou Dong,Deng Xu-Feng,Liu Quan-Xing,Dai Ji-Gang,Zheng HongORCID

Funder

National Natural Science Foundation of China

Excellent Talent Program of Chongqing

Key Project of Frontier Science Research of Chinese Academy of Sciences

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Cancer Research,Pharmacology,Toxicology,Oncology

Reference44 articles.

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4. Reck M, Schenker M, Lee KH, Provencio M, Nishio M, Lesniewski-Kmak K, Sangha R, Ahmed S, Raimbourg J, Feeney K, Corre R, Franke FA, Richardet E, Penrod JR, Yuan Y, Nathan FE, Bhagavatheeswaran P, DeRosa M, Taylor F, Lawrance R, Brahmer J (2019) Nivolumab plus ipilimumab versus chemotherapy as first-line treatment in advanced non–small-cell lung cancer with high tumour mutational burden: patient-reported outcomes results from the randomised, open-label, phase III CheckMate 227 trial. Eur J Cancer 116:137–147

5. Liu W-j, Du Y, Wen R, Yang M, Xu J (2020) Drug resistance to targeted therapeutic strategies in non-small cell lung cancer. Pharmacol Ther 206:107438

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