Role of TPMT and ITPA variants in mercaptopurine disposition
Author:
Funder
Kræftens bekæmpelse
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Cancer Research,Pharmacology,Toxicology,Oncology
Link
http://link.springer.com/article/10.1007/s00280-018-3525-8/fulltext.html
Reference45 articles.
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2. Liang DC, Yang CP, Liu HC, Jaing TH, Chen SH, Hung IJ et al (2016) NUDT15 gene polymorphism related to mercaptopurine intolerance in Taiwan Chinese children with acute lymphoblastic leukemia. Pharmacogenomics J 16(6):536–539
3. Moriyama T, Nishii R, Perez-Andreu V, Yang W, Klussmann FA, Zhao X et al (2016) NUDT15 polymorphisms alter thiopurine metabolism and hematopoietic toxicity. Nat Genet 48(4):367–373
4. Moriyama T, Nishii R, Lin TN, Kihira K, Toyoda H, Jacob N et al (2017) The effects of inherited NUDT15 polymorphisms on thiopurine active metabolites in Japanese children with acute lymphoblastic leukemia. Pharmacogenet Genomics 27(6):236–239
5. Suzuki H, Fukushima H, Suzuki R, Hosaka S, Yamaki Y, Kobayashi C et al (2016) Genotyping NUDT15 can predict the dose reduction of 6-MP for children with acute lymphoblastic leukemia especially at a preschool age. J Hum Genet 61(9):797–801
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