Neurotoxicity after high-dose methotrexate (MTX) is adequately explained by insufficient folinic acid rescue
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Cancer Research,Pharmacology,Toxicology,Oncology
Link
http://link.springer.com/article/10.1007/s00280-017-3304-y/fulltext.html
Reference72 articles.
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2. Duffner PK, Armstrong FD, Chen L, Helton KJ, Brecher ML, Bell B, Chauvenet AR (2014) Neurocognitive and neuroradiologic central nervous system late effects in children treated on pediatric oncology group (POG) P9605 (standard risk) and P9201 (lesser risk) acute lymphoblastic leukemia protocols (ACCL0131): a methotrexate consequence? A report from the Children’s Oncology Group. J Pediatr Hematol Oncol 36:8–15
3. Richards S, Pui CH, Gayon P, Childhood Acute Lymphoblastic Leukemia Collaborative Group (CALLCG) (2004) Systemic review and meta-analysis of randomized trials of central nervous system directed therapy for childhood acute lymphoblastic leukemia. Pediatr Blood Cancer 60:185–195
4. Larsen EC, Devidas M, Chen S et al (2016) Dexamethasone and high-dose methotrexate improve outcome for children and young adults with high-risk b-acute lymphoblastic leukemia: a report from Children’s Oncology Group Study AALL0232. J Clin Oncol 34:2380–2388
5. Cohen IJ (2004) Defining the appropriate dosage of folinic acid after high-dose methotrexate that will prevent neurotoxicity without rescuing malignant cells in the central nervous system. J Pediatr Hematol Oncol 26:156–163
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1. Late effects of high-dose methotrexate in childhood cancer survivors: a Swiss single centre observational study;Discover Oncology;2024-01-25
2. Clinico-radiological profile, management and follow-up of methotrexate induced neurotoxicity in children with acute lymphoblastic leukemia;Leukemia & Lymphoma;2023-08-11
3. A Rapid Method for Determination of Serum Methotrexate Using Ultra-High-Performance Liquid Chromatography–Tandem Mass Spectrometry and Its Application in Therapeutic Drug Monitoring;Journal of Laboratory Physicians;2023-01-18
4. A Comprehensive Review of Neuropsychologic Studies Supports the Concept That Adequate Folinic Acid Rescue Prevents Post Methotrexate Neurotoxicity;Journal of Pediatric Hematology/Oncology;2022-12-12
5. Reply to Ian J. Cohen;Supportive Care in Cancer;2022-01-19
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