Synergy of irofulven in combination with other DNA damaging agents: synergistic interaction with altretamine, alkylating, and platinum-derived agents in the MV522 lung tumor model

Author:

Kelner Michael J.,McMorris Trevor C.,Rojas Rafael J.,Estes Leita A.,Suthipinijtham Pharnuk

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Cancer Research,Pharmacology,Toxicology,Oncology

Reference39 articles.

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4. Friedman HS, Keir ST, Houghton PJ, Lawless AA, Bigner DD, Waters SJ (2001) Activity of irofulven (6-hydroxymethylacylfulvene) in the treatment of glioblastoma multiforme-derived xenografts in athymic mice. Cancer Chemother Pharmacol 48:413–416

5. Gong J, Vaidyanathan VG, Yu X, Kensler TW, Peterson LA, Sturla SJ (2007) Depurinating acylfulvene-DNA adducts: characterizing cellular chemical reactions of a selective antitumor agent. J Amer Chem Soc 129:2101–2111

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