Phase I clinical trial of lenalidomide in combination with bevacizumab in patients with advanced cancer

Author:

Said Rabih,Kakadiaris Eugenia,Piha-Paul Sarina,Fu Siqing,Falchook Gerald,Janku Filip,Wheler Jennifer J.,Zinner Ralph,Hong David S.,Kurzrock Razelle,Tsimberidou Apostolia M.

Funder

Celgene

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Cancer Research,Pharmacology,Toxicology,Oncology

Reference25 articles.

1. http://www.fda.gov/downloads/drugs/drugsafety/ucm111335.pdf . 2014

2. Muller GW, Chen R, Huang SY et al (1999) Amino-substituted thalidomide analogs: potent inhibitors of TNF-alpha production. Bioorg Med Chem Lett 9:1625–1630

3. Corral LG, Haslett PA, Muller GW et al (1999) Differential cytokine modulation and T cell activation by two distinct classes of thalidomide analogues that are potent inhibitors of TNF-alpha. J Immunol 163:380–386

4. Sharpe AH, Abbas AK (2006) T-cell costimulation—biology, therapeutic potential, and challenges. N Engl J Med 355:973–975

5. Segler A, Tsimberidou AM (2012) Lenalidomide in solid tumors. Cancer Chemother Pharmacol 69:1393–1406

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