Matrine induces caspase-dependent apoptosis in human osteosarcoma cells in vitro and in vivo through the upregulation of Bax and Fas/FasL and downregulation of Bcl-2-Reference-Cited by-同舟云学术

Matrine induces caspase-dependent apoptosis in human osteosarcoma cells in vitro and in vivo through the upregulation of Bax and Fas/FasL and downregulation of Bcl-2

Published:2011-06-30 Issue:2 Volume:69 Page:317-331
ISSN:0344-5704
Container-title:Cancer Chemotherapy and Pharmacology
language:en
Short-container-title:Cancer Chemother Pharmacol

Author:

Liang Cheng Zhen,Zhang Jia Kai,Shi Zhongli,Liu Bing,Shen Chengchun Q.,Tao Hui Min

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Cancer Research,Pharmacology,Toxicology,Oncology

Link

http://link.springer.com/content/pdf/10.1007/s00280-011-1699-4.pdf

Reference35 articles.

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3. Wittenburg LA, Bisson L, Rose BJ, Korch C, Thamm DH (2011) The histone deacetylase inhibitor valproic acid sensitizes human and canine osteosarcoma to doxorubicin. Cancer Chemother Pharmacol 67:83–92

4. Broker LE, Kruyt FA, Giaccone G (2005) Cell death independent of caspase: a review. Clin Cancer Res 11:3155–3162

5. Kim H, Rafiuddin-Shah M, Tu HC, Jeffers JR, Zambetti GP, Hsieh JJ, Cheng EH (2006) Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies. Nat Cell Biol 8:1348–1358

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