Relative bioavailability and food effect of the galectin-3 inhibitor selvigaltin (GB1211) administered as a tablet in healthy participants (GALBA-1)-Reference-Cited by-同舟云学术

Relative bioavailability and food effect of the galectin-3 inhibitor selvigaltin (GB1211) administered as a tablet in healthy participants (GALBA-1)

Published:2024-08-21 Issue: Volume: Page:
ISSN:0344-5704
Container-title:Cancer Chemotherapy and Pharmacology
language:en
Short-container-title:Cancer Chemother Pharmacol

Author:

Aslanis Vassilios^ORCID,Abd-Elaziz Khalid^ORCID,Slack Robert J.^ORCID,Brinch Anne,Gravelle Lise,Morley Wayne,Phung De,Herman Kimberly^ORCID,Holyer Ian,Poulsen Karen Killerup,Dogterom Peter,Tantawi Susan^ORCID,Zetterberg Fredrik R.^ORCID,Jacoby Brian,Schambye Hans,Lindmark Bertil

Funder

Galecto Biotech AB

Publisher

Springer Science and Business Media LLC

Link

https://link.springer.com/content/pdf/10.1007/s00280-024-04710-3.pdf

Reference22 articles.

1. Dong R, Zhang M, Hu Q, Zheng S, Soh A, Zheng Y, Yuan H (2018) Galectin-3 as a novel biomarker for disease diagnosis and a target for therapy (Review). Int J Mol Med 41(2):599–614. https://doi.org/10.3892/ijmm.2017.3311

2. Ho JE, Gao W, Levy D, Santhanakrishnan R, Araki T, Rosas IO, Hatabu H, Latourelle JC, Nishino M, Dupuis J, Washko GR, O’onnor GT, Hunninghake GM (2016) Galectin-3 is associated with restrictive lung disease and interstitial lung abnormalities. Am J Respir Crit Care Med 194(1):77–83. https://doi.org/10.1164/rccm.201509-1753OC

3. Ho JE, Liu C, Lyass A, Courchesne P, Pencina MJ, Vasan RS, Larson MG, Levy D (2012) Galectin-3, a marker of cardiac fibrosis, predicts incident heart failure in the community. J Am Coll Cardiol 60(14):1249–1256. https://doi.org/10.1016/j.jacc.2012.04.053

4. Henderson NC, Mackinnon AC, Farnworth SL, Poirier F, Russo FP, Iredale JP, Haslett C, Simpson KJ, Sethi T (2006) Galectin-3 regulates myofibroblast activation and hepatic fibrosis. Proc Natl Acad Sci USA 103(13):5060–5065. https://doi.org/10.1073/pnas.0511167103

5. Cervantes-Alvarez E, la Rosa NL, la Mora MS, Valdez-Sandoval P, Palacios-Jimenez M, Rodriguez-Alvarez F, Vera-Maldonado BI, Aguirre-Aguilar E, Escobar-Valderrama JM, Alanis-Mendizabal J, Mendez-Guerrero O, Tejeda-Dominguez F, Torres-Ruiz J, Gomez-Martin D, Colborn KL, Kershenobich D, Huang CA, Navarro-Alvarez N (2022) Galectin-3 as a potential prognostic biomarker of severe COVID-19 in SARS-CoV-2 infected patients. Sci Rep 12(1):1856. https://doi.org/10.1038/s41598-022-05968-4