Dose individualization of sunitinib in metastatic renal cell cancer: toxicity-adjusted dose or therapeutic drug monitoring

Author:

Sabanathan DhanushaORCID,Zhang Alison,Fox Peter,Coulter Sally,Gebski Val,Balakrishnar Bavanthi,Chan Mathew,Liddle Christopher,Gurney Howard

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Cancer Research,Pharmacology,Toxicology,Oncology

Reference38 articles.

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3. Motzer RJ, Hutson TE, Tomczak P, Michaelson MD, Bukowski RM, Oudard S, Negrier S, Szczylik C, Pili R, Bjarnason GA, Garcia-Del-Muro X, Sosman JA, Solska E, Wilding G, Thompson JA, Kim ST, Chen I, Huang X, Figlin RA (2009) Overall survival and updated results for sunitinib compared with interferon alfa in patients with metastatic renal cell carcinoma. J Clin Oncol 27(22):3584. doi: 10.1200/JCO.2008.20.1293

4. Motzer RJ, Hutson TE, Tomczak P, Michaelson MD, Bukowski RM, Rixe O, Oudard S, Negrier S, Szczylik C, Kim ST, Chen I, Bycott PW, Baum CM, Figlin RA (2007) Sunitinib versus interferon alfa in metastatic renal-cell carcinoma. N Engl J Med 356(2):115–124. doi: 10.1056/NEJMoa065044

5. Bracarda S, Iacovelli R, Rizzo M, Rossi M, Galli L, Procopio G, Longo F, Santoni M, Morelli F, Di Lorenzo G, Porta C, Camerini A, Di Bella S, Martignetti A, Gasparro D, Sabbatini R, Ceresoli G, Mosca A, Santini D, Boni L (2014) Retrospective observational study of sunitinib administered on schedule 2/1 in patients with metastatic renal cell carcinoma (mRCC): the rainbow study. J Clin Oncol 32(4):471

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