CNS penetration of the CDK4/6 inhibitor ribociclib in non-tumor bearing mice and mice bearing pediatric brain tumors
Author:
Funder
National Cancer Institute
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Cancer Research,Pharmacology,Toxicology,Oncology
Link
http://link.springer.com/content/pdf/10.1007/s00280-019-03864-9.pdf
Reference18 articles.
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3. Broniscer A, Iacono L, Chintagumpala M, Fouladi M, Wallace D, Bowers DC, Stewart C, Krasin MJ, Gajjar A (2005) Role of temozolomide after radiotherapy for newly diagnosed diffuse brainstem glioma in children: results of a multiinstitutional study (SJHG-98). Cancer (J) 103(1):133–139
4. Anon (2017) Ribociclib approved for advanced breast cancer. Cancer Discov 7(5):OF3. https://doi.org/10.1158/2159-8290.CD-NB2017-043
5. Sherr CJ (2016) A new cell-cycle target in cancer—inhibiting cyclin D-dependent kinases 4 and 6. N Engl J Med 375(20):1920–1923. https://doi.org/10.1056/NEJMp1612343
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