Pharmacodynamic properties of methotrexate and AminotrexateTM during weekly therapy

Author:

Cole Peter D.,Alcaraz María José,Smith Angela K.,Tan John,Kamen Barton A.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Cancer Research,Pharmacology,Toxicology,Oncology

Reference49 articles.

1. Angelis-Stoforidis P, Vajda FJ, Christophidis N (1999) Methotrexate polyglutamate levels in circulating erythrocytes and polymorphs correlate with clinical efficacy in rheumatoid arthritis. Clin Exp Rheumatol 17:313

2. Balinska M, Galivan J, Coward JK (1981) Efflux of methotrexate and its polyglutamate derivatives from hepatic cells in vitro. Cancer Res 41:2751

3. Bertino JR (1963) The mechanism of action of the folate antagonists in man. Cancer Res 23:1286

4. Bettachi CJ, Kamen BA, Cush JJ (1999) Post-methotrexate (MTX) CNS toxicity: symptom reduction with dextromethorphan. Arthritis Rheuma 42:S236

5. Bleyer WA, Dedrick RL (1977) Clinical pharmacology of intrathecal methotrexate I Pharmacokinetics in nontoxic patients after lumbar injection. Cancer Treat Rep 61:703

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