Novel formulation of abiraterone acetate might allow significant dose reduction and eliminates substantial positive food effect-Reference-Cited by-同舟云学术

Novel formulation of abiraterone acetate might allow significant dose reduction and eliminates substantial positive food effect

Published:2017-08-03 Issue:4 Volume:80 Page:723-728
ISSN:0344-5704
Container-title:Cancer Chemotherapy and Pharmacology
language:en
Short-container-title:Cancer Chemother Pharmacol

Author:

Solymosi Tamás,Ötvös Zsolt,Angi Réka,Ordasi Betti,Jordán Tamás,Molnár László,McDermott John,Zann Vanessa,Church Ann,Mair Stuart,Filipcsei Genovéva,Heltovics Gábor,Glavinas Hristos^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Cancer Research,Pharmacology,Toxicology,Oncology

Link

http://link.springer.com/article/10.1007/s00280-017-3406-6/fulltext.html

Reference11 articles.

1. Acharya M, Bernard A, Gonzalez M, Jiao J, De Vries R, Tran N (2012) Open-label, phase I, pharmacokinetic studies of abiraterone acetate in healthy men. Cancer Chemother Pharmacol 69(6):1583–1590

2. Attard G et al (2008) Phase I clinical trial of a selective inhibitor of CYP17, abiraterone acetate, confirms that castration-resistant prostate cancer commonly remains hormone driven. J Clin Oncol 26(28):4563–4571

3. EMA/CHMP/542871 (2011) Assessment report for Zytiga procedure no.: EMEA/H/C/002321. Assessment, vol. 44

4. Chi KN et al (2015) Food effects on abiraterone pharmacokinetics in healthy subjects and patients with metastatic castration-resistant prostate cancer. J Clin Pharmacol 55(12):1406–1414

5. Geboers S et al (2016) The effect of food on the intraluminal behavior of abiraterone acetate in man. J Pharm Sci 105(9):2974–2981

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