Effects of repeated oral doses of ketoconazole on a sequential ascending single oral dose of fedratinib in healthy subjects
Author:
Funder
Bristol-Myers Squibb
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Cancer Research,Pharmacology,Toxicology,Oncology
Link
http://link.springer.com/content/pdf/10.1007/s00280-020-04067-3.pdf
Reference19 articles.
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2. Schwartz DM, Bonelli M, Gadina M, O'Shea JJ (2016) Type I/II cytokines, JAKs, and new strategies for treating autoimmune diseases. Nat Rev Rheumatol 12(1):25–36. https://doi.org/10.1038/nrrheum.2015.167
3. Vainchenker W, Constantinescu SN (2013) JAK/STAT signaling in hematological malignancies. Oncogene 32(21):2601–2613. https://doi.org/10.1038/onc.2012.347
4. Romano M, Sollazzo D, Trabanelli S, Barone M, Polverelli N, Perricone M et al (2017) Mutations in JAK2 and Calreticulin genes are associated with specific alterations of the immune system in myelofibrosis. Oncoimmunology 6(10):e1345402. https://doi.org/10.1080/2162402X.2017.1345402
5. U.S. Food and Drug Administration. INREBIC (fedratinib) label. https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/212327s000lbl.pdf. Accessed 12 Nov 2019
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