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PLGA nanoparticle formulation of RK-33: an RNA helicase inhibitor against DDX3

  • Published:2015-09-02 Issue:4 Volume:76 Page:821-827
  • ISSN:0344-5704
  • Container-title:Cancer Chemotherapy and Pharmacology
  • language:en
  • Short-container-title:Cancer Chemother Pharmacol

Author:

Bol Guus Martinus,Khan Raheela,Heerma van Voss Marise Rosa,Tantravedi Saritha,Korz Dorian,Kato Yoshinori,Raman Venu

Funder

KWF Kankerbestrijding

Congressionally Directed Medical Research Programs

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Cancer Research,Pharmacology,Toxicology,Oncology

Reference26 articles.

1. Bol GM, Vesuna F, Xie M, Zeng J, Aziz K, Gandhi N, Levine A, Irving A, Korz D, Tantravedi S, Heerma van Voss MR, Gabrielson K, Bordt EA, Polster BM, Cope L, van der Groep P, Kondaskar A, Rudek MA, Hosmane RS, van der Wall E, van Diest PJ, Tran PT, Raman V (2015) Targeting DDX3 with a small molecule inhibitor for lung cancer therapy. EMBO Mol Med 7(5):648–649. doi: 10.15252/emmm.201404368

2. Bol GM, Raman V, van der Groep P, Vermeulen JF, Patel AH, van der Wall E, van Diest PJ (2013) Expression of the RNA helicase DDX3 and the hypoxia response in breast cancer. PLoS ONE 8:e63548. doi: 10.1371/journal.pone.0063548

3. Botlagunta M, Krishnamachary B, Vesuna F, Winnard PT Jr, Bol GM, Patel AH, Raman V (2011) Expression of DDX3 is directly modulated by hypoxia inducible factor-1 alpha in breast epithelial cells. PLoS ONE 6:e17563. doi: 10.1371/journal.pone.0017563

4. Pugh TJ, Weeraratne SD, Archer TC, Pomeranz Krummel DA, Auclair D, Bochicchio J, Carneiro MO, Carter SL, Cibulskis K, Erlich RL, Greulich H, Lawrence MS, Lennon NJ, McKenna A, Meldrim J, Ramos AH, Ross MG, Russ C, Shefler E, Sivachenko A, Sogoloff B, Stojanov P, Tamayo P, Mesirov JP, Amani V, Teider N, Sengupta S, Francois JP, Northcott PA, Taylor MD, Yu F, Crabtree GR, Kautzman AG, Gabriel SB, Getz G, Jager N, Jones DT, Lichter P, Pfister SM, Roberts TM, Meyerson M, Pomeroy SL, Cho YJ (2012) Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations. Nature 488:106–110. doi: 10.1038/nature11329

5. Huang JS, Chao CC, Su TL, Yeh SH, Chen DS, Chen CT, Chen PJ, Jou YS (2004) Diverse cellular transformation capability of overexpressed genes in human hepatocellular carcinoma. Biochem Biophys Res Commun 315:950–958. doi: 10.1016/j.bbrc.2004.01.151
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