Metagenomic Analysis Reveals Previously Undescribed Bat Coronavirus Strains in Eswatini
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Published:2021-12
Issue:4
Volume:18
Page:421-428
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ISSN:1612-9202
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Container-title:EcoHealth
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language:en
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Short-container-title:EcoHealth
Author:
Shapiro Julie TeresaORCID, Mollerup Sarah, Jensen Randi Holm, Olofsson Jill Katharina, Nguyen Nam-phuong D., Hansen Thomas Arn, Vinner Lasse, Monadjem Ara, McCleery Robert A., Hansen Anders J.
Abstract
AbstractWe investigated the prevalence of coronaviruses in 44 bats from four families in northeastern Eswatini using high-throughput sequencing of fecal samples. We found evidence of coronaviruses in 18% of the bats. We recovered full or near-full-length genomes from two bat species: Chaerephon pumilus and Afronycteris nana, as well as additional coronavirus genome fragments from C. pumilus, Epomophorus wahlbergi, Mops condylurus, and Scotophilus dinganii. All bats from which we detected coronaviruses were captured leaving buildings or near human settlements, demonstrating the importance of continued surveillance of coronaviruses in bats to better understand the prevalence, diversity, and potential risks for spillover.
Funder
National Institutes of Health National Science Foundation Bat Conservation International Innovationsfonden University of Florida Biodiversity Institute Fellowship
Publisher
Springer Science and Business Media LLC
Subject
Health, Toxicology and Mutagenesis,Ecology
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