Distribution of SC-4453, a new semi-synthetic derivative of digoxin, following an infusion preceded by an iv loading dose in the guinea-pig. Binding to plasma proteins

Author:

Randimbivololona F.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology

Reference25 articles.

1. Godfraind T., Tona Lutete N. (1979): Inhibition of the (Na+-K+ )ATPase isolated from human heart, guineapig heart and guinea-pig brain. Eur. J. Pharmacol.60, 329–335.

2. Godfraind T., Ghysel-Burton J. (1979): The cardioactive properties of SC-4453, a digoxin analogue with C17, β-pyridazine ring. Eur. J. Pharmacol.60, 337–344.

3. Randimbivololona F., Lesne M. (1983): Comparison of the pharmacokinetic parameters of digoxin and SC-4453 a digoxin analogue, following a single bolus IV dose and following an infusion preceeded by an IV loading dose in the guinea-pig. J. Pharmacol. (Paris)14, 9–17.

4. Marzo A., Ghirardi P., Casagrande C., Jellife R.W. (1983): The pharmacokinetic behavior of SC-4453, a new cardiac glycoside, and digoxin in the dog. Drug Exp. Clin. Res.IX, 207–212.

5. Harrisson C.E., Brandeburg R.O., Ongley P.A., Orvis A.L., Owen C.A., (1966): The distribution and excretion of trftiated substances in experimental animal following the administration of 3H-digoxin. J. Lab. Clin. Med.67, 764–777.

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