Growth hormone directly favors hepatic ketogenesis in persons with prediabetes or type 2 diabetes mellitus treated with empagliflozin
Author:
Publisher
Springer Science and Business Media LLC
Subject
Endocrinology,Endocrinology, Diabetes and Metabolism
Link
https://link.springer.com/content/pdf/10.1007/s12020-021-02730-0.pdf
Reference17 articles.
1. T. Heise, E. Seewaldt-Becker, S. Macha, S. Hantel, S. Pinnetti, L. Seman et al. Safety, tolerability, pharmacokinetics and pharmacodynamics following 4 weeks’ treatment with empagliflozin once daily in patients with type 2 diabetes. Diabetes Obes. Metab. 15, 613–21 (2013). https://doi.org/10.1111/dom.12073
2. C. Bonner, J. Kerr-Conte, V. Gmyr, G. Queniat, E. Moerman, J. Thévenet et al. Inhibition of the glucose transporter SGLT2 with dapagliflozin in pancreatic alpha cells triggers glucagon secretion. Nat. Med. 21, 512–7 (2015). https://doi.org/10.1038/nm.3828
3. H. Qiu, A. Novikov, V. Vallon, Ketosis and diabetic ketoacidosis in response to SGLT2 inhibitors: basic mechanisms and therapeutic perspectives. Diabetes Metab. Res. Rev. 33, 1–9 (2017). https://doi.org/10.1002/dmrr.2886
4. N. Moøller, J.O.L. Joørgensen, Effects of growth hormone on glucose, lipid, and protein metabolism in human subjects. Endocr. Rev. 30, 152–77 (2009). https://doi.org/10.1210/er.2008-0027
5. D. RABINOWITZ, K.L. ZIERLER, A metabolic regulating device based on the actions of human growth hormone and of insulin, singly and together, on the human forearm. Nature 199, 913–5 (1963). https://doi.org/10.1038/199913a0
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