Abstract
AbstractHabituation refers to the physiological adaptation to recurrent stressors, which can be measured by cortisol levels, and is considered a central mechanism in reducing allostatic load. Resilience, a potential factor influencing stress reduction, is the focus of this study. Specifically, the study aims to investigate the impact of resilience, as assessed by the Brief Resilience Scale (BRS), on habituation. The Trier Social Stress Test (TSST) was used as the recurrent stressor, and it was administered to each of the 56 subjects at 4 consecutive measurements. To assess habituation, various physiological parameters including the area under the curve with respect to the ground (AUCg) and with respect to the increase (AUCi), cortisol peak, slope from baseline to peak, and recovery were calculated. Mixed linear models were employed to examine the differences in the influence of resilience on habituation across the different time points. The findings indicate that the influence of resilience significantly varies from the first to the fourth measurement time point for AUCg (p = .048), while no significant differences were observed for the other cortisol parameters. The effects plot suggests that individuals with higher levels of resilience exhibit lower AUCg values throughout the measurements. These findings provide initial evidence supporting resilience as a predictor of cortisol habituation. However, future studies should also consider dynamic resilience models, utilizing longitudinally assessed resilience as a predictor for habituation, to explore whether resilience acts as a determinant of habituation or if habituation itself constitutes a resilience mechanism.
Funder
Horizon 2020 Framework Programme
Universitätsmedizin der Johannes Gutenberg-Universität Mainz
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Biological Psychiatry,Psychiatry and Mental health,General Medicine
Reference51 articles.
1. Chmitorz A, Kurth K, Mey LK, Wenzel M, Lieb K, Tüscher O, Kubiak T, Kalisch R (2020) Assessment of microstressors in adults: questionnaire development and ecological validation of the mainz inventory of microstressors. JMIR Ment Health. https://doi.org/10.2196/14566
2. Die Techniker (2016) Entspann dich, Deutschland. TK-Stressstudie 2016. https://www.tk.de/resource/blob/2026630/9154e4c71766c410dc859916aa798217/tk-stressstudie-2016-data.pdf. Accessed 24 Jan 2022
3. Sterling P, Eyer J (1988) Allostasis: a new paradigm to explain arousal pathology. In: Fisher J, Reason J (eds) Handbook of life stress, cognition, and health. John Wiley & Sons Inc., New Jersey, pp 629–649
4. McEwen BS (2017) Neurobiological and systemic effects of chronic stress. Chronic Stress. https://doi.org/10.1177/2470547017692328
5. McEwen BS, Stellar E (1993) Stress and the individual. Arch Intern Med 153(18):2093–2101