One-year efficacy of a lifestyle behavioural intervention on physical and mental health in people with severe mental disorders: results from a randomized controlled trial

Author:

Luciano M.ORCID,Sampogna G.,D’Ambrosio E.,Rampino A.,Amore M.,Calcagno P.,Rossi A.,Rossi R.,Carmassi C.,Dell’Osso L.,Bianciardi E.,Siracusano A.,Della Rocca Bianca,Di Vincenzo M.,Del Vecchio Valeria,Malangone Claudio,Mancuso Emiliana,Toni Claudia,Volpicelli Antonio,Andriola Ileana,Selvaggi Pierluigi,Belvederi Murri Martino,Di Stefano Ramona,Pacitti Francesca,Dell’Oste Valerio,Fantasia Sara,Pedrinelli Virginia,Di Lorenzo Giorgio,Niolu Cinzia,Fiorillo A.,

Abstract

AbstractThis multicentric randomized controlled trial (RCT), carried out in six Italian University mental health sites, aims to test the efficacy of a six-month psychosocial intervention (LYFESTYLE) on Body Mass Index (BMI), body weight, waist circumference, fasting glucose, triglycerides, cholesterol, Framingham and HOmeostasis Model Assessment of insulin resistance (HOMA-IR) indexes in patients with schizophrenia, bipolar disorder, and major depression. Moreover, the efficacy of the intervention has also been tested on several other physical and mental health domains. Patients were randomly allocated to receive the six-month experimental intervention (LIFESTYLE) or a behavioural control intervention. All enrolled patients were assessed at baseline and after one year. We recruited 401 patients (206 in the experimental and 195 in the control group) with a diagnosis of schizophrenia or other psychotic disorder (29.9%), bipolar disorder (43.3%), or major depression (26.9%). At one year, patients receiving the experimental intervention reported an improvement in body mass index, body weight, waist circumference, HOMA-IR index, anxiety and depressive symptoms and in quality of life. Our findings confirm the efficacy of the LIFESTYLE intervention in improving physical and mental health-related outcomes in patients with severe mental illnesses after one year.

Funder

Ministero dell'Università e della Ricerca

Open access funding provided by Università degli Studi della Campania Luigi Vanvitelli within the CRUICARE Agreement.

Università degli Studi della Campania Luigi Vanvitelli

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Biological Psychiatry,Psychiatry and Mental health,General Medicine

Reference70 articles.

1. Kim H, Turiano NA, Forbes MK, Kotov R, Krueger RF, Eaton NR, Workgroup HU (2021) Internalizing psychopathology and all-cause mortality: a comparison of transdiagnostic vs. diagnosis-based risk prediction. World Psychiatry 20:276–282. https://doi.org/10.1002/wps.20859

2. Correll CU, Solmi M, Croatto G, Schneider LK, Rohani-Montez SC, Fairley L, Smith N, Bitter I, Gorwood P, Taipale H, Tiihonen J (2022) Mortality in people with schizophrenia: a systematic review and meta-analysis of relative risk and aggravating or attenuating factors. World Psychiatry 21:248–271. https://doi.org/10.1002/wps.20994

3. Sampogna G, Di Vincenzo M, Della Rocca B, Mancuso E, Volpicelli A, Perris F, Del Vecchio V, Giallonardo V, Luciano M, Fiorillo A (2022) Physical comorbidities in patients with severe mental disorders: a brief narrative review on current challenges and practical implications for professionals. Riv Psichiatr 57:251–257. https://doi.org/10.1708/3922.39071

4. Luciano M, Sampogna G, Amore M, Andriola I, Calcagno P, Carmassi C, Del Vecchio V, Dell’Osso L, Di Lorenzo G, Gelao B, Giallonardo V, Rossi A, Rossi R, Siracusano A, Fiorillo A, LIFESTYLE Working Group (2021) How to improve the physical health of people with severe mental illness? A multicentric randomized controlled trial on the efficacy of a lifestyle group intervention. Eur Psychiatry 64:e72. https://doi.org/10.1192/j.eurpsy.2021.2253

5. Suokas K, Hakulinen C, Sund R, Kampman O, Pirkola S (2022) Mortality in persons with recent primary or secondary care contacts for mental disorders in Finland. World Psychiatry 21:470–471. https://doi.org/10.1002/wps.21027

Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3