Structure of a gap junction gene: Rat connexin-32-Reference-Cited by-同舟云学术

Structure of a gap junction gene: Rat connexin-32

Published:1988-10-01 Issue:5 Volume:8 Page:455-464
ISSN:0144-8463
Container-title:Bioscience Reports
language:en
Short-container-title:

Author:

Miller Todd¹,Dahl Gerhard¹,Werner Rudolf¹

Affiliation:

1. Department of Biochemistry and Molecular Biology and Physiology and Biophysics, University of Miami, P.O. Box 016129, Miami, FL 33101, USA

Abstract

A genomic clone for the rat liver gap junction protein (connexin-32) was isolated and characterized by restriction enzyme mapping and sequence analysis. While the complete coding sequence is contained within one uninterrupted block, the 5′-untranslated region of the transcript contains a 6.1 kb intron. Both S1 nuclease protection and primer extension assays indicate multiple transcription start sites. Sequences homologous to cAMP response elements are found near the transcription start sites and within the 3′-end of the intron.

Publisher

Portland Press Ltd.

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Link

https://portlandpress.com/bioscirep/article-pdf/8/5/455/472276/bsr0080455.pdf

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