Research and study of 2-((4,6 dimethyl pyrimidine-2-yle) thio)-N-phenyl acetamide derivatives as inhibitors of sirtuin 2 protein for the treatment of cancer using QSAR, molecular docking and molecular dynamic simulation
Author:
Publisher
Springer Science and Business Media LLC
Subject
Computational Theory and Mathematics,Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Computer Science Applications,Catalysis
Link
https://link.springer.com/content/pdf/10.1007/s00894-022-05288-4.pdf
Reference50 articles.
1. Seyfried TN, Flores RE, Poff AM, D’Agostino DP (2014) Cancer as a metabolic disease: implications for novel therapeutics. Carcinogenesis. https://doi.org/10.1093/carcin/bgt480
2. Seyfried TN, Shelton LM (2010) Cancer as a metabolic disease. Nutr Metab. https://doi.org/10.1186/1743-7075-7-7
3. Mei Zh, Zhang X, Yi J, Huang J, He J, Tao Y (2016) Sirtuins in metabolism, DNA repair, and cancer. J Exp Clin Cancer Res. https://doi.org/10.1186/s13046-016-0461-5
4. Hoffmann G, Breitenbücher F, Schuler M, Ehrenhofer-Murray AE (2014) A Novel Sirtuin 2 (SIRT2) Inhibitor with p53-dependent Pro-apoptotic Activity in Non-small Cell Lung Cancer. J Biol Chem. https://doi.org/10.1074/jbc.M113.487736
5. Lee IH (2019) Mechanisms and disease implications of sirtuin-mediated autophagic regulation. Exp Mol Med. https://doi.org/10.1038/s12276-019-0302-7
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3