How does nintedanib overcome cancer drug-resistant mutation of RET protein-tyrosine kinase: insights from molecular dynamics simulations-Reference-Cited by-同舟云学术

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How does nintedanib overcome cancer drug-resistant mutation of RET protein-tyrosine kinase: insights from molecular dynamics simulations

Published:2021-11 Issue:11 Volume:27 Page:
ISSN:1610-2940
Container-title:Journal of Molecular Modeling
language:en
Short-container-title:J Mol Model

Author:

Cao Shu,Jiang Xu,Tan Changbin,Fu Ming,Xiong Wenqing,Ji Dong,Lv Jun

Publisher

Springer Science and Business Media LLC

Subject

Computational Theory and Mathematics,Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Computer Science Applications,Catalysis

Link

https://link.springer.com/content/pdf/10.1007/s00894-021-04964-1.pdf

Reference54 articles.

1. Roskoski R (2021) Properties of FDA-approved small molecule protein kinase inhibitors: A 2021 update. Pharmacol Res 165:105463

2. Ding C, Song Z, Shen A et al (2020) Small molecules targeting the innate immune cGAS-STING-TBK1 signaling pathway. Acta Pharm Sin B 10:2272–2298

3. Ward RA, Fawell S, Floc’h N, et al (2020) Challenges and opportunities in Cancer Drug Resistance. Chem Rev 121:3297–3351

4. Ni D, Li Y, Qiu Y et al (2020) Combining allosteric and orthosteric drugs to overcome drug resistance. Trends Pharmacol Sci 41:336–348

5. Lu S, Qiu Y, Ni D et al (2020) Emergence of allosteric drug-resistance mutations: new challenges for allosteric drug discovery. Drug Discov Today 25:177–184

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