Targeting the SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) with synthetic/designer unnatural nucleoside analogs: an in silico study

Author:

Bag Subhendu Sekhar,Sinha Sayantan,Dutta Soumya,Baishya Hirak Jyoti,Paul Suravi

Funder

Department of Science and Technology

Department of Biotechnology, Ministry of Science and Technology, India

Publisher

Springer Science and Business Media LLC

Subject

Computational Theory and Mathematics,Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Computer Science Applications,Catalysis

Reference34 articles.

1. Bag SS, Sinha S, Saito I (2020) A systematic review of the efficacy and safety of favipiravir (Avigan) for the treatment of novel COVID-19 infections. Med Res Arch 8:24

2. Bag SS (2020) The role of blood biomarkers to indicate the clinical severity of COVID-19 prognosis. Biomarkers J 7:74

3. Bag SS, Sinha S (2022) Affinity toward Mucormycosis in COVID-19 patients. Int J Adv Res Biol Sci 9:21–28

4. Chowdhury T, Roymahapatra G, Mandal SM (2021) In silico identification of a potent arsenic based approved drug darinaparsin against SARS-CoV-2: inhibitor of RNA dependent RNA polymerase (RdRp) and essential proteases. Infect Disord Targets (Formerly Curr Drug Targets-Infectious Disord 21:608–618

5. Hall DC Jr, Ji H-F (2020) A search for medications to treat COVID-19 via in silico molecular docking models of the SARS-CoV-2 spike glycoprotein and 3CL protease. Travel Med Infect Dis 35:101646

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