Insights into pralsetinib resistance to the non-gatekeeper RET kinase G810C mutation through molecular dynamics simulations-Reference-Cited by-同舟云学术

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Insights into pralsetinib resistance to the non-gatekeeper RET kinase G810C mutation through molecular dynamics simulations

Published:2022-12-28 Issue:1 Volume:29 Page:
ISSN:1610-2940
Container-title:Journal of Molecular Modeling
language:en
Short-container-title:J Mol Model

Author:

Cao Shu,Tan Changbin,Fei Anhua,Hu Gangqiang,Fu Ming,Lv Jun

Publisher

Springer Science and Business Media LLC

Subject

Computational Theory and Mathematics,Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Computer Science Applications,Catalysis

Link

https://link.springer.com/content/pdf/10.1007/s00894-022-05429-9.pdf

Reference63 articles.

1. Roskoski R, Sadeghi-Nejad A (2018) Role of RET protein-tyrosine kinase inhibitors in the treatment RET-driven thyroid and lung cancers. Pharmacol Res 128:1–17. https://doi.org/10.1016/j.phrs.2017.12.021

2. Ferrara R, Auger N, Auclin E, Besse B (2018) Clinical and translational implications of RET rearrangements in non–small cell lung cancer. J Thorac Oncol 13:27–45. https://doi.org/10.1016/j.jtho.2017.10.021

3. Romei C, Ciampi R, Elisei R (2016) A comprehensive overview of the role of the RET proto-oncogene in thyroid carcinoma. Nat Rev Endocrinol 12:192–202. https://doi.org/10.1038/nrendo.2016.11

4. Salvatore D, Santoro M, Schlumberger M (2021) The importance of the RET gene in thyroid cancer and therapeutic implications. Nat Rev Endocrinol 17:296–306. https://doi.org/10.1038/s41574-021-00470-9

5. Rosen EY, Won HH, Zheng Y et al (2022) The evolution of RET inhibitor resistance in RET-driven lung and thyroid cancers. Nat Commun 13:1450. https://doi.org/10.1038/s41467-022-28848-x

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